ReviewJournal of endocrinological investigation2019
Clinical features, diagnosis and therapy of pituicytoma: an update.
Review in Journal of endocrinological investigation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Primary tumors of the posterior pituitary: A systematic review.Reviews in endocrine & metabolic disorders · 2019Pooled it
- Histopathological Types, Clinical Presentation, Imaging Studies, Treatment Strategies, and Prognosis of Posterior Pituitary Tumors: An Updated Review.Journal of clinical medicine · 2025Review
- Machine learning method based on radiomics help differentiate posterior pituitary tumors from pituitary neuroendocrine tumors and craniopharyngioma.Scientific reports · 2025Article
- Clinical, surgical, and endocrine outcome following treatment of posterior pituitary tumors: a retrospective cohort study.Pituitary · 2025Article
- Posterior transpetrosal approach to a suprasellar retroinfundibular pituicytoma: A case report and comprehensive literature review.Brain & spine · 2025Article
- Oncocytic pituicytoma in a patient with Cushing's disease: a case report and narrative literature review.Frontiers in endocrinology · 2025Review
- Sustained Response to Brigatinib in an Aggressive Relapsing Atypical Pituicytoma With ELM4-ALK Fusion.JCO precision oncology · 2024Article
- Intraventricular pituicytoma: illustrative case.Journal of neurosurgery. Case lessons · 2024Article
- A Rare Pituitary Tumor.Cureus · 2024Article
- Surgical approach to the treatment of pituicytoma. Report of five cases and a literature review.World neurosurgery: X · 2023Article
- Surgical management of pituicytomas: a single-center case series.Acta neurologica Belgica · 2023Article
- Pituicytoma: A rare tumor of the sella. A case report and review of literature for diagnosis and management.Surgical neurology international · 2023Article
- Pituicytoma Associated with Suspected Cushing's Disease: Two Case Reports and a Literature Review.Journal of clinical medicine · 2022Article
- Dabrafenib monotherapy for a recurrent BRAFV600E-mutated TTF-1-positive posterior pituitary tumor.Acta neurochirurgica · 2022Article
- Treatment and prognostic factors of pituicytoma: a single-center experience and comprehensive literature review.Pituitary · 2021Review
- A Rare Case of Pituicytoma Presenting Cystic Formation.Brain tumor research and treatment · 2021Article
- Clinical features, radiological profiles, pathological features and surgical outcomes of pituicytomas: a report of 11 cases and a pooled analysis of individual patient data.Military Medical Research · 2021Article
- Diversity of Pathological Conditions Affecting Pituitary Stalk.Journal of clinical medicine · 2021Article
- Infectious Complications of Expanded Endoscopic Transsphenoidal Surgery: A Retrospective Cohort Analysis of 100 Cases.Journal of neurological surgery. Part B, Skull base · 2020Article
- Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPituicytomas (PTs) are extremely rare, low-grade glial tumors closely related to the neurohypophyseal axis. Definite conclusions concerning the optimal diagnostic and therapeutic approach to these neoplasms are lacking to date, as most of this information has been presented as case reports.
methodsRetrospective review of case reports published in the scientific literature to date, including a new illustrative example treated in our department.
results116 cases were collected. PTs had a higher prevalence in the fifth and sixth decades of life, with a slight male predominance. Main symptoms, which tended to be progressive, included visual field defects and pituitary-hypothalamic dysfunction. Radiologically, PTs were found anywhere along the hypothalamic-pituitary axis mimicking other, more frequent tumors growing in this anatomical region. Surgical treatment included both transcranial or transsphenoidal approaches, and resulted in gross total resection and morbidity rates of 46.8 and 59%, respectively; the latter essentially consisted in anterior and posterior pituitary dysfunction, with limited impact on daily quality of life.
conclusionsDue to both low frequency and the absence of pathognomonic clinical and/or radiological features, formulating a suspicion diagnosis of PT represents a considerable challenge even for experienced professionals. The indication for treatment should be made on an individual basis, but it is inescapable in the presence of a visual field defect. The surgical approach has to be tailored according to the topography of the tumor and preoperative symptoms; the greatest challenges in accomplishing a gross total removal are represented by the degree of adherence and vascularization of the PT.
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