Evidence map›Paper›PMID 30030695›Full record

ArticleSleep & breathing = Schlaf & Atmung2019

Sleep quality in survivors of critical illness.

Ch Alexopoulou, M Bolaki, E Akoumianaki, S Erimaki, E Kondili, P Mitsias, D Georgopoulos

Abstract read
PubMed Publisher
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Observational
  3. Article
  4. Sleep and critical illness: a review.Frontiers in medicine · 2023
    Review
  5. Article
  6. Mechanisms of Post-critical Illness Cardiovascular Disease.Frontiers in cardiovascular medicine · 2022
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Sleep and Wakefulness Evaluation in Critically Ill Patients. One Step Forward.American journal of respiratory and critical care medicine · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Ch AlexopoulouIntensive Care Medicine Department, University Hospital of Heraklion, Medical School, University of Crete, Heraklion, Greece.
M BolakiDepartment of Pulmonary Medicine, University Hospital of Heraklion, Medical School, University of Crete, Heraklion, Greece.
E AkoumianakiIntensive Care Medicine Department, University Hospital of Heraklion, Medical School, University of Crete, Heraklion, Greece.
S ErimakiNeurology Department, University Hospital of Heraklion, Medical School, University of Crete, Heraklion, Greece.
E KondiliIntensive Care Medicine Department, University Hospital of Heraklion, Medical School, University of Crete, Heraklion, Greece.
P MitsiasNeurology Department, University Hospital of Heraklion, Medical School, University of Crete, Heraklion, Greece.
D GeorgopoulosIntensive Care Medicine Department, University Hospital of Heraklion, Medical School, University of Crete, Heraklion, Greece. georgopd@uoc.gr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThere is limited data regarding the sleep quality in survivors of critical illness, while the time course of the sleep abnormalities observed after ICU discharge is not known. The aim of this study was to assess sleep quality and the time course of sleep abnormalities in survivors of critical illness.

methodsEligible survivors of critical illness without hypercapnia and hypoxemia were evaluated within 10 days (1st evaluation, n = 36) and at 6 months after hospital discharge (2nd evaluation, n = 29). At each visit, all patients underwent an overnight full polysomnography and completed health-related quality of life questionnaires (HRQL). Lung function and electro-diagnostic tests (ED) were performed in 24 and 11 patients, respectively.

resultsAt 1st evaluation, sleep quality and HRQL were poor. Sleep was characterised by high percentages of N1, low of N3 and REM stages, and high apnea-hypopnea index (AHI, events/h). Twenty-two out of 36 patients (61%) exhibited AHI ≥ 15 (21 obstructive, 1 central). None of the patients' characteristics, including HRQL and lung function, predicted the occurrence of AHI ≥ 15. At 6 months, although sleep quality remained poor (high percentages of N1 and low of REM), sleep architecture had improved as indicated by the significant increase in N3 [4.2% (0-12.5) vs. 9.8% (3.0-20.4)] and decrease in AHI [21.5 (6.5-29.4) vs. 12.8 (4.7-20.4)]. HRQL improved slightly but significantly at 6 months. Neither the changes in HRQL nor in lung function tests were related to these of sleep architecture. Six out of eight patients with abnormal ED at 1st evaluation continued to exhibit abnormal results at 6 months.

conclusionsSurvivors of critical illness exhibited a high prevalence of obstructive sleep-disordered breathing and poor sleep architecture at hospital discharge, which slightly improved 6 months later, indicating that reversible factors are partly responsible for these abnormalities.

Indexed as

Critical IllnessSurvivorsAdultAgedCritical CareFemaleFollow-Up StudiesHumansMaleMiddle AgedPolysomnographyPrevalenceQuality of LifeSleep Apnea, ObstructiveSleep, REMSleep Wake DisordersHospital dischargeIntensive care unitMechanical ventilationPolysomnographyQuality of lifeSleep architecture

Identifiers

PMID30030695

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.