ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2018
Molecular epidemiology of virulence and antimicrobial resistance determinants in Klebsiella pneumoniae from hospitalised patients in Kilimanjaro, Tanzania.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 23 citations in OpenAlex.
- Molecular characterisation of extended-Spectrum-Beta-lactamase-producingOne health (Amsterdam, Netherlands) · 2026Article
- SeqAfrica: empowering Africa's fight against antimicrobial resistance through genomics.Frontiers in public health · 2025Article
- Phage-antibiotic combinations againstFrontiers in microbiology · 2025Article
- Comprehensive genomics reveals novel sequence types of multidrug resistant Klebsiella oxytoca with uncharacterized capsular polysaccharide K- and lipopolysaccharide O-antigen loci from the National Hospital of Uganda.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2024Article
- Phenotypic and Genotypic Characterization of Extended Spectrum Beta-Lactamase-Producing Clinical Isolates ofInternational journal of microbiology · 2024Article
- Within-patient and global evolutionary dynamics ofMicrobial genomics · 2023Article
- Human pandemic K27-ST392 CTX-M-15 extended-spectrum β-lactamase-positiveOne health (Amsterdam, Netherlands) · 2022Article
- Antimicrobial Resistance and Virulence Characteristics ofPathogens (Basel, Switzerland) · 2022Article
- NGSocomial Infections: High-Resolution Views of Hospital-Acquired Infections Through Genomic Epidemiology.Journal of the Pediatric Infectious Diseases Society · 2021Review
- Clones and Clusters of Antimicrobial-Resistant Klebsiella From Southwestern Nigeria.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Effective Photodynamic Therapy with Ir(III) for Virulent Clinical Isolates of Extended-Spectrum Beta-LactamasePharmaceutics · 2021Article
- NovelFrontiers in microbiology · 2021Article
- ResFinder 4.0 for predictions of phenotypes from genotypes.The Journal of antimicrobial chemotherapy · 2020Article
- Genomic Epidemiology of an Outbreak ofInfection and drug resistance · 2020Article
- Status and potential of bacterial genomics for public health practice: a scoping review.Implementation science : IS · 2019Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
This study aimed to use whole-genome sequencing to determine virulence and antimicrobial resistance genes in K. pneumoniae isolated from patients in a tertiary care hospital in Kilimanjaro. K. pneumoniae isolates from patients attending Kilimanjaro Christian Medical Centre between August 2013 and August 2015 were fully genome-sequenced and analysed locally. Sequence analysis was done for identification of virulence and AMR genes. Plasmid and multi-locus sequence typing and capsular or capsular (K) typing were performed and phylogeny was done to ascertain K. pneumoniae relatedness. Stata 13 (College Station, TX, 77845, USA) was used to determine Cohen's kappa coefficient of agreement between the phenotypically tested and sequence-predicted resistance. A total of 16 (47.1%) sequence types (STs) and 10 (29.4%) K types were identified in 30 (88.2%) and 17 (50.0%) of all analysed isolates, respectively. K. pneumoniae ST17 were 6 (17.6%). The commonest determinants were bla
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