Evidence map›Paper›PMID 30030649›Full record

ReviewCurrent urology reports2018

Castration-Resistant Prostate Cancer: Sequencing Oral and Infusion Agents.

Sarah Bennett Starosta, Stephen J Savage

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current urology reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sarah Bennett StarostaDepartment of Urology, Medical University of South Carolina, 96 Jonathan Lucas St. CSB 644, Charleston, SC, 29425, USA.
Stephen J SavageDepartment of Urology, Medical University of South Carolina, 96 Jonathan Lucas St. CSB 644, Charleston, SC, 29425, USA. savages@musc.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewTo update treatment options and considerations for castration-resistant prostate cancer with specific attention to sequencing of agents based on available evidence and treatment rationale. RECENT

findingsThe newest research developments over the last several years include multicenter studies that address the sequencing of therapies to improve the treatment of metastatic castration-resistant prostate cancer. Chemotherapy agents, as well as androgen receptor antagonists, are evolving, and there are new tests available to define which patients are more likely to benefit. In addition, there have been some additional trials looking into the safety and efficacy of combination treatment and new therapies. There are multiple factors that should be considered to determine the sequence and/or combinations of therapies for metastatic castration-resistant prostate cancer that can improve quality of life and survival. Promising novel agents in combination with personalized medicine will likely continue to improve treatment of these patients.

Indexed as

Administration, OralAndrogen Receptor AntagonistsAntineoplastic AgentsClinical Trials as TopicCombined Modality TherapyHumansImmunotherapyInfusions, IntravenousMaleMolecular Targeted TherapyProstatic Neoplasms, Castration-ResistantRadiopharmaceuticalsAndrogen Receptor AntagonistsAntineoplastic AgentsRadiopharmaceuticalsCastration-resistantNovel androgen-directed therapiesProstate cancerTreatment sequence

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.