Evidence map›Paper›PMID 30030486›Full record

ArticleScientific reports2018

Prevascularization of dermal substitutes with adipose tissue-derived microvascular fragments enhances early skin grafting.

Florian S Frueh, Thomas Später, Christina Körbel, Claudia Scheuer, Anna C Simson, Nicole Lindenblatt, Pietro Giovanoli, Michael D Menger, Matthias W Laschke

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 57 citations in OpenAlex.

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  9. [Research advances on stem cell-based treatments in animal studies and clinical trials of lymphedema].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Florian S FruehInstitute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg/Saar, Germany. florian.frueh@usz.ch.ORCID 0000-0003-0904-9591
Thomas SpäterInstitute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg/Saar, Germany.
Christina KörbelInstitute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg/Saar, Germany.
Claudia ScheuerInstitute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg/Saar, Germany.
Anna C SimsonInstitute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg/Saar, Germany.
Nicole LindenblattDivision of Plastic Surgery and Hand Surgery, University Hospital Zürich, University of Zürich, 8091, Zürich, Switzerland.
Pietro GiovanoliDivision of Plastic Surgery and Hand Surgery, University Hospital Zürich, University of Zürich, 8091, Zürich, Switzerland.
Michael D MengerInstitute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg/Saar, Germany.
Matthias W LaschkeInstitute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg/Saar, Germany.
Saarland University · DEUniversity of Zurich · CHUniversity Hospital of Zurich · CH

Funding

Universität des Saarlandes (Saarland University) HOMFOR 2017
6 · The paper itself

Abstract

Split-thickness skin grafts (STSG) are still the gold standard for the treatment of most skin defects. Hence, there is an ongoing need to improve this procedure. For this purpose, we herein analyzed dermal matrices seeded with adipose tissue-derived microvascular fragments (ad-MVF) in a bradythrophic wound model. In additional experiments, the matrices were covered with autologous STSG 10 days after implantation. Green fluorescence protein (GFP)

Indexed as

LymphangiogenesisNeovascularization, PhysiologicWound HealingAdipose TissueAnimalsMiceMice, Inbred C57BLMicrovesselsModels, BiologicalPhotoacoustic TechniquesSkin, ArtificialSkin TransplantationTransplants

Identifiers

PMID30030486
PMCPMC6054621
OpenAlexW2883748172

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.