Evidence map›Paper›PMID 30030432›Full record

ArticleNature communications2018

Concerted pulsatile and graded neural dynamics enables efficient chemotaxis in C. elegans.

Eyal Itskovits, Rotem Ruach, Alexander Kazakov, Alon Zaslaver

Erratum issuedAbstract read
In one paragraph

Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. ThebioRxiv : the preprint server for biology · 2026
    Article
  3. TAXISCAN, Optimizing throughput and behavioral depth in standardbioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Ectopic transcription due to inherited histone methylation may interfere with the ongoing function of differentiated neurons.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  8. Aberrant neuronal hyperactivation causes an age-dependent behavioral decline inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Microfluidic-AssistedCyborg and bionic systems (Washington, D.C.) · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Microswimmers learning chemotaxis with genetic algorithms.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Eyal ItskovitsDepartment of Genetics, The Silberman Institute of Life Science, Edmond J. Safra Campus, the Hebrew University of Jerusalem, Jerusalem, Israel.ORCID http://orcid.org/0000-0002-7285-2988
Rotem RuachDepartment of Genetics, The Silberman Institute of Life Science, Edmond J. Safra Campus, the Hebrew University of Jerusalem, Jerusalem, Israel.
Alexander KazakovEdmond and Lily Safra Center for Brain Sciences, the Hebrew University of Jerusalem, Jerusalem, Israel.
Alon ZaslaverDepartment of Genetics, The Silberman Institute of Life Science, Edmond J. Safra Campus, the Hebrew University of Jerusalem, Jerusalem, Israel. alonzas@mail.huji.ac.il.

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Council for Higher Education of Israel | Israeli Centers for Research Excellence (I-CORE) 1902/12EC | European Research Council (ERC) ‎336803‎Israel Science Foundation (ISF) ‎1259/13‎Israel Science Foundation (ISF) ‎1300/17‎NIH HHS P40 OD010440
6 · The paper itself

Abstract

The ability of animals to effectively locate and navigate toward food sources is central for survival. Here, using C. elegans nematodes, we reveal the neural mechanism underlying efficient navigation in chemical gradients. This mechanism relies on the activity of two types of chemosensory neurons: one (AWA) coding gradients via stochastic pulsatile dynamics, and the second (AWC

Indexed as

AnimalsBehavior, AnimalCaenorhabditis elegansCaenorhabditis elegans ProteinsChemotaxisComputer SimulationMicrofluidicsMovementNeuronsSignal TransductionSpecies SpecificityCaenorhabditis elegans Proteins

Identifiers

PMID30030432
PMCPMC6054637

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.