ArticleNature communications2018
TIGIT
Abstract read
In one paragraph
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
73 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials.Lancet (London, England) · 2020Pooled it
- Expanding the supply of human leukocytes for research by harvesting cell concentrates from Trima Accel tubing sets.Scientific reports · 2026Article
- Recent progress in macrophage-mediated tendon injury and healing.Histology and histopathology · 2026Review
- The Myeloid-T Lymphocyte Axis in Chronic Lung Allograft Rejection: Emerging Insights into the Immune Circuitry Driving Fibrosis.Results and problems in cell differentiation · 2026Review
- Review
- Innovative approaches targeting innate immune cells to promote organ transplant tolerance.Frontiers in transplantation · 2026Review
- M2 macrophage polarization in allogeneic skin transplantation: from intrinsic mechanisms to clinical prospects for immune tolerance.Molecular biology reports · 2025Review
- Potential Biomarkers of Therapeutic Response to ECP in Solid Organ Transplantation.Transplantation direct · 2025Article
- Unravelling γδ T-cell dysregulation in the gut and its implications for immune-mediated diseases.Disease models & mechanisms · 2025Article
- Potential Impact of Extracorporeal Photopheresis on Trained Immunity and Organ Transplant Acceptance.Transplantation direct · 2025Article
- Unraveling the Roles of Macrophages in Vascularized Composite Allotransplantation.Biomedicines · 2025Review
- Platelet apheresis with additive solution and plasma rinseback affects the cellular composition of LRS chamber products.Scientific reports · 2025Article
- Functional diversity of cardiac macrophages in health and disease.Nature reviews. Cardiology · 2025Review
- Immunoregulatory iPSC-derived non-lymphoid progeny in autoimmunity and GVHD alloimmunity.Stem cells (Dayton, Ohio) · 2025Review
- Peritoneal resident macrophages constitute an immunosuppressive environment in peritoneal metastasized colorectal cancer.Nature communications · 2025Article
- Prostate cancer immunotherapy-based strategies: an updated review emphasizing immune checkpoint inhibitors.Frontiers in immunology · 2025Review
- Regulatory cell therapy for kidney transplantation and autoimmune kidney diseases.Pediatric nephrology (Berlin, Germany) · 2025Review
- Pig regulatory macrophages as a donor-derived immune modulators in xenotransplantation.Frontiers in immunology · 2025Article
- Characterization of the phenotype and function of PRELPFrontiers in genetics · 2025Article
- Heterozygous BTNL8 variants in individuals with multisystem inflammatory syndrome in children (MIS-C).The Journal of experimental medicine · 2024Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on byM2018
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Authors and funding
18 authors.
Paloma RiquelmeDepartment of Surgery, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, Regensburg, 93053, Germany.ORCID http://orcid.org/0000-0001-8962-3156
Jan HaarerDepartment of Surgery, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, Regensburg, 93053, Germany.
Anja KammlerDepartment of Surgery, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, Regensburg, 93053, Germany.
Lisa WalterDepartment of Surgery, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, Regensburg, 93053, Germany.ORCID http://orcid.org/0000-0003-3421-2362
Stefan TomiukMiltenyi Biotec GmbH, Friedrich-Ebert-Str. 68, 51429, Bergisch Gladbach, Germany.
Norbert AhrensTransfusion Medicine, Institute for Clinical Chemistry, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, 93053, Regensburg, Germany.ORCID http://orcid.org/0000-0002-4680-2688
Anja K WegeDepartment of Gynecology and Obstetrics, University Medical Center Regensburg, Landshuter Straße 65, 93053, Regensburg, Germany.ORCID http://orcid.org/0000-0002-8838-0532
Ivan GoeczeDepartment of Surgery, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, Regensburg, 93053, Germany.
Daniel ZecherDepartment of Nephrology, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, 93053, Regensburg, Germany.
Bernhard BanasDepartment of Nephrology, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, 93053, Regensburg, Germany.ORCID http://orcid.org/0000-0003-2076-2195
Rainer SpangDepartment of Statistical Bioinformatics, Institute for Functional Genomics, University of Regensburg, Am BioPark 9, 93053, Regensburg, Germany.
Fred FändrichDepartment of Surgery, University Hospital Schleswig-Holstein, Arnold-Heller-Straße 3, 24015, Kiel, Germany.
Manfred B LutzInstitute for Virology and Immunobiology, University of Würzburg, Versbacher Str. 7, 97078, Würzburg, Germany.
Birgit SawitzkiInstitute for Medical Immunology, Berlin Charité University Hospital, Augustenburger Platz 1, 13353, Berlin, Germany.
Hans J SchlittDepartment of Surgery, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, Regensburg, 93053, Germany.ORCID http://orcid.org/0000-0002-3874-0296
Jordi OchandoInmunología de Trasplantes, Centro Nacional de Microbiología, Cta. Majadahonda-Pozuelo Km 2, 28220, Madrid, Spain.ORCID http://orcid.org/0000-0001-7037-1681
Edward K GeisslerDepartment of Surgery, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, Regensburg, 93053, Germany.
James A HutchinsonDepartment of Surgery, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, Regensburg, 93053, Germany. james.hutchinson@klinik.uni-regensburg.de.ORCID http://orcid.org/0000-0002-1199-4210
Funding
Deutsche Forschungsgemeinschaft (German Research Foundation) HU 1838/1-1Deutsche Forschungsgemeinschaft (German Research Foundation) HU 1838/2-1
Abstract
Human regulatory macrophages (Mreg) have shown early clinical promise as a cell-based adjunct immunosuppressive therapy in solid organ transplantation. It is hypothesised that recipient CD4
Indexed as
AllograftsAnimalsCell DifferentiationDendritic CellsForkhead Transcription FactorsGraft RejectionHumansInterleukin-10Kidney TransplantationLipopolysaccharide ReceptorsMacrophagesMicePhenotypeReceptors, ImmunologicSignal TransductionT-Lymphocytes, RegulatoryForkhead Transcription FactorsFOXP3 protein, humanIL10 protein, humanInterleukin-10Lipopolysaccharide ReceptorsReceptors, ImmunologicTIGIT protein, humanTransforming Growth Factor beta
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.