Evidence map›Paper›PMID 30030382›Full record

ArticleThe Journal of biological chemistry2018

Gluconeogenic precursor availability regulates flux through the glyoxylate shunt in

Audrey Crousilles, Stephen K Dolan, Paul Brear, Dimitri Y Chirgadze, Martin Welch

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 69 citations in OpenAlex.

  1. Article
  2. Article
  3. DesertPlants (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. An allantoin-inducible glyoxylate utilization pathway inMicrobiology (Reading, England) · 2025
    Article
  9. Review
  10. Study on the phosphorylation of NADJournal of enzyme inhibition and medicinal chemistry · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Two Different Isocitrate Dehydrogenases fromInternational journal of molecular sciences · 2023
    Article
  19. Article
  20. Redox-Controlled Shunts in a Synthetic Chemical Reaction Cycle.Journal of the American Chemical Society · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Audrey CrousillesFrom the Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW, United Kingdom.
Stephen K DolanFrom the Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW, United Kingdom.ORCID 0000-0002-7391-2137
Paul BrearFrom the Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW, United Kingdom.
Dimitri Y ChirgadzeFrom the Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW, United Kingdom.
Martin WelchFrom the Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW, United Kingdom mw240@cam.ac.uk.ORCID 0000-0003-3646-1733
University of Cambridge · GB

Funding

Biotechnology and Biological Sciences Research Council BB/M019411/1
6 · The paper itself

Abstract

The glyoxylate shunt bypasses the oxidative decarboxylation steps of the tricarboxylic acid (TCA) cycle, thereby conserving carbon skeletons for gluconeogenesis and biomass production. In

Indexed as

GluconeogenesisAcetyl Coenzyme ACitric Acid CycleCrystallography, X-RayDecarboxylationEscherichia coliGlyoxylatesIsocitrate DehydrogenaseIsocitrate LyaseKineticsOxaloacetic AcidPhosphorylationPseudomonas aeruginosaAcetyl Coenzyme AGlyoxylatesglyoxylic acidIsocitrate DehydrogenaseIsocitrate LyaseOxaloacetic Acidacetyl coenzyme A (acetyl-CoA)allosteric regulationbacterial metabolismbacterial pathogenesisbacterial virulenceenzyme regulationenzyme structuregluconeogenesisglyoxylate shuntisocitrate dehydrogenaseisocitrate lyasemetabolic adaptationmetabolic regulationpost-translational modification (PTM)Pseudomonas aeruginosatricarboxylic acid cycle (TCA cycle) (Krebs cycle)

Identifiers

PMID30030382
PMCPMC6139552
OpenAlexW2883059728

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.