ArticleThe Journal of biological chemistry2018
Oligosaccharides from depolymerized fucosylated glycosaminoglycan: Structures and minimum size for intrinsic factor Xase complex inhibition.
Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 54 citations in OpenAlex.
- High molecular weight fucosylated glycosaminoglycan promotes the binding of antithrombin and thrombin: a template mechanism and structure-activity relationship study.Glycoconjugate journal · 2025Article
- Article
- Structural Characterization and Anticoagulant Potential ofMarine drugs · 2025Article
- Purification and Structural Analyses of Sulfated Polysaccharides from Low-Value Sea CucumberMarine drugs · 2024Article
- Branched Chondroitin Sulfate Oligosaccharides Derived from the Sea CucumberMarine drugs · 2022Article
- Critical Quality Control Methods for a Novel Anticoagulant Candidate LFG-Na by HPSEC-MALLS-RID and Bioactivity Assays.Molecules (Basel, Switzerland) · 2022Article
- Fucose-Rich Sulfated Polysaccharides from Two Vietnamese Sea CucumbersMarine drugs · 2022Article
- Physicochemical Properties and Anticoagulant Activity of Purified Heteropolysaccharides fromMolecules (Basel, Switzerland) · 2022Article
- Semisynthetic Isomers of Fucosylated Chondroitin Sulfate Polysaccharides with Fucosyl Branches at a Non-Natural Site.Biomacromolecules · 2021Article
- Structural Characterization and Heparanase Inhibitory Activity of Fucosylated Glycosaminoglycan fromMarine drugs · 2021Article
- Marine Antithrombotics.Marine drugs · 2020Review
- (Semi)-Synthetic Fucosylated Chondroitin Sulfate Oligo- and Polysaccharides.Marine drugs · 2020Review
- A Study for the Access to a Semi-synthetic Regioisomer of Natural Fucosylated Chondroitin Sulfate with Fucosyl Branches onMarine drugs · 2019Article
- Physicochemical Characteristics and Anticoagulant Activities of the Polysaccharides from Sea CucumberMarine drugs · 2019Article
- Precise Structure and Anticoagulant Activity of Fucosylated Glycosaminoglycan fromMarine drugs · 2019Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fucosylated glycosaminoglycan (FG), a structurally complex glycosaminoglycan found up to now exclusively in sea cucumbers, has distinct anticoagulant properties, notably a strong inhibitory activity of intrinsic factor Xase complex (FXase). Knowledge of the FG structures could facilitate the development of a clinically effective intrinsic FXase inhibitor for anticoagulant drugs. Here, a new fucosylated glycosaminoglycan was obtained from the widely traded sea cucumber
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