Evidence map›Paper›PMID 30030367›Full record

ArticlePediatrics2018

Factors Associated With Refusal of Intramuscular Vitamin K in Normal Newborns.

Jaspreet Loyal, James A Taylor, Carrie A Phillipi, Neera K Goyal, Kelly E Wood, Carl Seashore, Beth King, Eve Colson, Veronika Shabanova, Eugene D Shapiro and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Jaspreet LoyalDepartment of Pediatrics, Yale University, New Haven, Connecticut; jaspreet.loyal@yale.edu.
James A TaylorDepartment of Pediatrics, University of Washington, Seattle, Washington.
Carrie A PhillipiDepartment of Pediatrics, Oregon Health and Science University, Portland, Oregon.
Neera K GoyalDepartment of Pediatrics, Nemours, Philadelphia, Pennsylvania.
Kelly E WoodStead Family Department of Pediatrics, University of Iowa Stead Family Children's Hospital, Iowa City, Iowa.
Carl SeashoreDepartment of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and.
Beth KingAcademic Pediatric Association, McLean, Virginia.
Eve ColsonDepartment of Pediatrics, Yale University, New Haven, Connecticut.
Veronika ShabanovaDepartment of Pediatrics, Yale University, New Haven, Connecticut.
Eugene D ShapiroDepartment of Pediatrics, Yale University, New Haven, Connecticut.
BORN investigators
Yale University · USAcademic Pediatric Association · USOregon Health & Science University · USUniversity of Iowa Stead Family Children’s Hospital · USUniversity of North Carolina at Chapel Hill · USUniversity of Washington · US

Funding

Yale University Clinical and Translational Science Award ProgramUL1TR000142 · NCATS · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2012 to 2015
$31.8M
NCATS NIH HHS UL1 TR000142
6 · The paper itself

Abstract

BACKGROUND AND

objectiveRefusal of intramuscular (IM) vitamin K administration by parents is an emerging problem. Our objective was to assess the frequency of and factors associated with refusal of IM vitamin K administration in well newborns in the United States.

methodsWe determined the number of newborns admitted to well newborn units whose parents refused IM vitamin K administration in the Better Outcomes through Research for Newborns network and, in a nested patient-control study, identified factors associated with refusal of IM vitamin K administration by using a multiple logistic regression model.

resultsOf 102 878 newborns from 35 Better Outcomes through Research for Newborns sites, parents of 638 (0.6%) refused IM vitamin K administration. Frequency of refusal at individual sites varied from 0% to 2.3%. Exclusive breastfeeding (adjusted odds ratio [aOR] = 3.4; 95% confidence interval [CI]: 2.1-5.5), non-Hispanic white race and/or ethnicity (aOR = 1.7; 95% CI: 1.2-2.4), female sex (aOR = 1.6; 95% CI: 1.2-2.3), gestational age (aOR = 1.2; 95% CI: 1.1-1.4), and mother's age (aOR = 1.05; 95% CI: 1.02-1.08) were significantly associated with refusal of IM vitamin K administration. Refusal of the administration of both ocular prophylaxis and hepatitis B vaccine was also strongly associated with refusal of IM vitamin K administration (aOR = 88.7; 95% CI: 50.4-151.9).

conclusionsRefusal of IM vitamin K by parents of newborns is a significant problem. Interventions to minimize risks to these newborns are needed.

Indexed as

AdolescentAdultFemaleHumansInfant, NewbornInjections, IntramuscularMaleMiddle AgedParentsTreatment RefusalUnited StatesVitamin KVitamin K Deficiency BleedingYoung AdultVitamin K

Identifiers

PMID30030367
PMCPMC6317553
OpenAlexW2884978854

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.