Evidence map›Paper›PMID 30030338›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2019

Advancing Targeted Radionuclide Therapy Through the National Cancer Institute's Small Business Innovation Research Pathway.

Kaveh Zakeri, Deepa Narayanan, Greg Evans, Pataje Prasanna, Jeffrey C Buchsbaum, Bhadrasain Vikram, Jacek Capala

Abstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Radionuclide-based theranostics - a promising strategy for lung cancer.European journal of nuclear medicine and molecular imaging · 2023
    Review
  2. National Cancer Institute support for targeted alpha-emitter therapy.European journal of nuclear medicine and molecular imaging · 2021
    Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kaveh ZakeriRadiation Research Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, Maryland.
Deepa NarayananSmall Business Innovation Research Development Center, National Cancer Institute, Bethesda, Maryland.
Greg EvansSmall Business Innovation Research Development Center, National Cancer Institute, Bethesda, Maryland.
Pataje PrasannaRadiation Research Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, Maryland.
Jeffrey C BuchsbaumRadiation Research Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, Maryland.
Bhadrasain VikramRadiation Research Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, Maryland.
Jacek CapalaRadiation Research Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, Maryland capalaj@mail.nih.gov.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs of the National Cancer Institute (NCI) are congressionally mandated set-aside programs that provide research funding to for-profit small businesses for the development of innovative technologies and treatments that serve the public good. These two programs have an annual budget of $159 million (in 2017) and serve as the NCI's main engine of innovation for developing and commercializing cancer technologies. In collaboration with the NCI's Radiation Research Program, the NCI SBIR Development Center published in 2015-2017 three separate requests for proposals from small businesses for the development of systemic targeted radionuclide therapy (TRT) technologies to treat cancer. TRT combines a cytotoxic radioactive isotope with a molecularly targeted agent to produce an anticancer therapy capable of treating local or systemic disease. This article summarizes the NCI SBIR funding solicitations for the development of TRTs and the research proposals funded through them.

Indexed as

InventionsMolecular Targeted TherapyNational Cancer Institute (U.S.)Small BusinessHumansNeoplasmsResearch DesignUnited Statesoncologyradionuclide therapyradiopharmaceuticalssmall business innovation researchtargeted radionuclide therapytheranostics

Identifiers

PMID30030338
PMCPMC6910624

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.