Evidence map›Paper›PMID 30030323›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

Human Extrafollicular CD4

Sang Taek Kim, Jin-Young Choi, Begona Lainez, Vincent P Schulz, David E Karas, Eric D Baum, Jennifer Setlur, Patrick G Gallagher, Joe Craft

Abstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Oligoclonal CD4Communications biology · 2024
    Article
  11. Review
  12. Review
  13. Memory T follicular helper cells drive donor-specific antibodies independent of memory B cells and primary germinal center and alloantibody formation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2023
    Article
  14. Review
  15. Targeting TNature immunology · 2022
    Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Sang Taek KimRheumatology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06520.
Jin-Young ChoiRheumatology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06520.ORCID 0000-0002-7867-2427
Begona LainezRheumatology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06520.
Vincent P SchulzDepartment of Pediatrics, Yale School of Medicine, New Haven, CT 06520.
David E KarasOtolaryngology, Department of Surgery, Yale School of Medicine, New Haven, CT 06520.ORCID 0000-0002-5248-1497
Eric D BaumOtolaryngology, Department of Surgery, Yale School of Medicine, New Haven, CT 06520.
Jennifer SetlurOtolaryngology, Department of Surgery, Yale School of Medicine, New Haven, CT 06520.
Patrick G GallagherDepartment of Pediatrics, Yale School of Medicine, New Haven, CT 06520.
Joe CraftRheumatology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06520; joseph.craft@yale.edu.ORCID 0000-0002-1368-6756
Yale University · USThe University of Texas MD Anderson Cancer Center · US

Funding

TRAINING PROGRAM IN INVESTIGATIVE RHEUMATOLOGYT32AR007107 · NIAMS · YALE UNIVERSITY · PI RICHARD J BUCALA · 1986 to 2026
$7.5M
IMMUNE RESPONSES IN LUPUSR37AR040072 · NIAMS · YALE UNIVERSITY · PI CRAFT, JOSEPH EDGAR · 2000 to 2025
$7.4M
Yale Rheumatic Diseases Research Core CenterP30AR053495 · NIAMS · YALE UNIVERSITY · PI SHLOMCHIK, WARREN D · 2007 to 2017
$7.0M
Cis Regulatory Elements and Systemic Lupus ErythematosusR01AR068994 · NIAMS · YALE UNIVERSITY · PI CRAFT, JOSEPH EDGAR, GALLAGHER, PATRICK G · 2016 to 2020
$2.7M
NIAMS NIH HHS P30 AR053495NIAMS NIH HHS R01 AR068994NIAMS NIH HHS R37 AR040072NIAMS NIH HHS T32 AR007107
6 · The paper itself

Abstract

Follicular helper T (Tfh) cells are necessary for germinal center B cell maturation during primary immune responses; however, the T cells that promote humoral recall responses via memory B cells are less well defined. In this article, we characterize a human tonsillar CD4

Indexed as

Antibody FormationImmunologic MemoryAdolescentB-LymphocytesChildChild, PreschoolCytokinesFemaleGene Expression RegulationHumansImmunoglobulin GMaleProgrammed Cell Death 1 ReceptorProto-Oncogene Proteins c-bcl-6Receptors, CXCR5T-Lymphocytes, Helper-InducerBCL6 protein, humanCXCR5 protein, humanCytokinesImmunoglobulin GPDCD1 protein, humanProgrammed Cell Death 1 ReceptorProto-Oncogene Proteins c-bcl-6Receptors, CXCR5

Identifiers

PMID30030323
PMCPMC6112860
OpenAlexW2883231926

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.