ArticleBMJ case reports2018
Acute oesophageal necrosis: a rare but potentially fatal association of cocaine use.
Article in BMJ case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Markers of Prognosis for Acute Esophageal Necrosis: A Systematic Review.Digestive diseases (Basel, Switzerland) · 2025Pooled it
- Gastrointestinal complications of cocaine use: a narrative literature review.Frontiers in gastroenterology (Lausanne, Switzerland) · 2026Review
- Article
- Necrotizing Esophagitis: A Big Squeeze?Journal of the Canadian Association of Gastroenterology · 2022Article
- Article
- The Black Esophagus.Cureus · 2021Article
- Sudden Esophageal Necrosis and Mediastinitis Associated with Invasive Candidiasis: A Case Report.The American journal of case reports · 2021Article
- Cocaine-induced mesenteric ischaemia requiring small bowel resection.BMJ case reports · 2021Article
- Acute Esophageal Necrosis Early after Renal Transplantation.Case reports in nephrology · 2021Article
- Black esophagus: a syndrome of acute esophageal necrosis associated with active alcohol drinking.BMJ open gastroenterology · 2020Review
- A Case of Black Esophagus.Cureus · 2019Article
- Comprehensive review of acute oesophageal necrosis.BMJ case reports · 2019Article
- Diagnosis and management of acute esophageal necrosis.Annals of gastroenterologyReview
- Black esophagus.Autopsy & case reportsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute oesophageal necrosis (AON), also known as 'black oesophagus', is a rare condition characterised by the necrosis of the oesophagus usually involving the distal part. It has been associated with various conditions, and the pathogenesis is thought to involve hypovolaemia combined with decreased function of oesophageal protective mucosal barriers and may be compounded by the effect of gastric secretions on oesophageal mucosa. The hallmark of this condition is characteristic circumferential black discolouration of the distal oesophagus that may extend proximally. We present a case of a man who presented with haematemesis associated with cocaine abuse. Oesophagogastroduodenoscopy confirmed black oesophagus. The patient was managed with intravenous fluids, packed red blood cell transfusions, proton pump inhibitors and sucralfate suspension; however, he failed to recover. We have also reviewed the previous reported cases of AON in association with cocaine use.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.