Evidence map›Paper›PMID 30030230›Full record

ArticleApplied and environmental microbiology2018

Single-Homology-Arm Linear DNA Recombination by the Nonhomologous End Joining Pathway as a Novel and Simple Gene Inactivation Method: a Proof-of-Concept Study in

Shelian Lu, Yong Nie, Meng Wang, Hong-Xiu Xu, Dong-Ling Ma, Jie-Liang Liang, Xiao-Lei Wu

Open access · bronzeAbstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Shelian Lu *College of Engineering, Peking University, Beijing, People's Republic of China.
Yong Nie *College of Engineering, Peking University, Beijing, People's Republic of China.
Meng WangCollege of Engineering, Peking University, Beijing, People's Republic of China.
Hong-Xiu XuCollege of Architecture and Environment, Sichuan University, Chengdu, People's Republic of China.
Dong-Ling MaCollege of Engineering, Peking University, Beijing, People's Republic of China.
Jie-Liang LiangCollege of Engineering, Peking University, Beijing, People's Republic of China.
Xiao-Lei WuCollege of Engineering, Peking University, Beijing, People's Republic of China xiaolei_wu@pku.edu.cn.
Peking University · CN

Funding

Ethanol and glutamatergic transmission in the dorsal striatumR01AA021505 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WANG, JUN · 2012 to 2016
$1.4M
NIAAA NIH HHS R01 AA021505
6 · The paper itself

Abstract

Nonhomologous end joining (NHEJ) is critical for genome stability because of its roles in double-strand break repair. Ku and ligase D (LigD) are the crucial proteins in this process, and strains expressing Ku and LigD can cyclize linear DNA

Indexed as

DNA End-Joining RepairGene SilencingRecombination, GeneticActinomycetalesBacterial ProteinsDNA-Binding ProteinsGene EditingGenome, BacterialPlasmidsBacterial ProteinsDNA-Binding Proteinsgene inactivationnonhomologous end joiningsingle-homology-arm linear DNA

Identifiers

PMID30030230
PMCPMC6146981
OpenAlexW2949212734

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.