Evidence map›Paper›PMID 30029639›Full record

ArticleLipids in health and disease2018

Serum lipophilic antioxidants levels are associated with leucocyte telomere length among US adults.

Mohsen Mazidi, Andre Pascal Kengne, L J Cheskin, Maciej Banach

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In one paragraph

Article in Lipids in health and disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mohsen MazidiDepartment of Biology and Biological Engineering, Food and Nutrition Science, Chalmers University of Technology, SE-412 96, Gothenburg, Sweden. moshen@genetics.ac.cn.
Andre Pascal KengneNon-Communicable Disease Research Unit, South African Medical Research Council and University of Cape Town, Cape Town, South Africa.
L J CheskinDepartment of Health, Johns Hopkins Weight Management Center Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Maciej BanachDepartment of Hypertension, Chair of Nephrology and Hypertension, Medical University of Lodz, Lodz, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo examine the association between serum concentrations of antioxidant and telomere length (TL) in U.S adults.

methodsParticipants of the National Health and Nutrition Examination Survey (NHANES) with data available on TL measures from 2001 to 2002 were included. Serum lipophilic antioxidants level was measured using high performance liquid chromatography with photodiode array detection. We used analysis of co-variance and multivariable-adjusted linear regression models, accounting for the survey design and sample weights.

resultsOf the 5992 eligible participants, 47.5% (n = 2844) were men. The mean age was 46.9 years overall, 47.2 years in men and 46.6 in women (p = 0.071). In age, sex, race, education, marital status, adiposity, smoking, C-reactive protein adjusted linear regressions, antioxidant, serum α-carotene, trans-β-carotene, cis- β-carotene, β-cryptoxanthin and combined Lutein/zeaxanthin were positively and significantly associated with TL (all p < 0.001).

conclusionsOur findings support a possible positive association between serum concentrations of lipophylic antioxidant and TL. The implications of this association deserve further investigation.

Indexed as

TelomereAdultAntioxidantsbeta CaroteneBeta-CryptoxanthinCarotenoidsFemalegamma-TocopherolHumansLeukocytesMaleMiddle AgedNutritional StatusNutrition SurveysUnited StatesZeaxanthinsalpha-caroteneAntioxidantsbeta CaroteneBeta-CryptoxanthinCarotenoidsgamma-TocopherolZeaxanthinsAntioxidantNational health and nutrition examination surveyTelomere length

Identifiers

PMID30029639
PMCPMC6054751

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.