Evidence map›Paper›PMID 30029246›Full record

ArticleJournal of biomechanical engineering2018

Acute Surgical Injury Alters the Tensile Properties of Thoracolumbar Fascia in a Porcine Model.

Erika Nelson-Wong, Michal Glinka, Mamiko Noguchi, Helene Langevin, Gary J Badger, Jack P Callaghan

Open access · bronzeAbstract read
In one paragraph

Article in Journal of biomechanical engineering, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Erika Nelson-WongSchool of Physical Therapy, Regis University, 3333 Regis Boulevard G4, Denver, CO 80221 e-mail: .
Michal GlinkaFaculty of Applied Health Sciences, University of Waterloo, 200 University Avenue West, Waterloo, ON N2 L 3G1, Canada e-mail: .
Mamiko NoguchiFaculty of Applied Health Sciences, University of Waterloo, , Waterloo, ON N2 L 3G1, Canada e-mail: .
Helene LangevinOsher Center for Integrative Medicine at Harvard Medical School and Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115 e-mail: .
Gary J BadgerDepartment of Medical Biostatistics, College of Medicine, University of Vermont, Burlington, VT 05405 e-mail: .
Jack P CallaghanFaculty of Applied Health Sciences, University of Waterloo, , Waterloo, ON N2 L 3G1, Canada e-mail: .
University of Waterloo · CABrigham and Women's Hospital · USRegis University · USUniversity of Vermont Medical Center · US

Funding

Connective tissue and nervous system mechanisms of CAM therapies for low back paiR01AT004400 · NCCIH · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI LANGEVIN, HELENE M · 2011 to 2015
$1.9M
NCCIH NIH HHS R01 AT004400
6 · The paper itself

Abstract

Recent work utilizing ultrasound imaging demonstrated that individuals with low back pain (LBP) have increased thickness and decreased mobility of the thoracolumbar fascia (TLF), an indication that the TLF may play a role in LBP. This study used a porcine injury model (microsurgically induced local injury)-shown to produce similar results to those observed in humans with LBP-to test the hypothesis that TLF mechanical properties may also be altered in patients with LBP. Perimuscular TLF tissue was harvested from the noninjured side of vertebral level L3-4 in pigs randomized into either control (n = 5) or injured (n = 5) groups. All samples were tested with a displacement-controlled biaxial testing system using the following protocol: cyclic loading/unloading and stress relaxation tests at 25%, 35%, and then 45% of their resting length. Tissue anisotropy was also explored by comparing responses to loading in longitudinal and transverse orientations. Tissues from injured pigs were found to have greater stretch-stretch ratio moduli (measure of tissue stiffness), less energy dissipation, and less stress decay compared to tissues from control pigs. Responses across these variables also depended on loading orientation. CLINICAL SIGNIFICANCE: these findings suggest that a focal TLF injury can produce impairments in tissue mechanical properties away from the injured area itself. This could contribute to some of the functional abnormalities observed in human LBP.

Indexed as

Lumbar VertebraeTensile StrengthThoracic VertebraeAnimalsAnisotropyBiomechanical PhenomenaFasciaStress, MechanicalSwine

Identifiers

PMID30029246
PMCPMC6993774
OpenAlexW2810360060

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.