Evidence map›Paper›PMID 30028848›Full record

ArticlePloS one2018

A low-noise silicon nitride nanopore device on a polymer substrate.

Wook Choi, Eun-Seok Jeon, Kyoung-Yong Chun, Young-Rok Kim, Kyeong-Beom Park, Ki-Bum Kim, Chang-Soo Han

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Wook ChoiSchool of Mechanical Engineering, College of Engineering, Korea University, Anam-Dong, Seongbuk-Gu, Seoul, Korea.
Eun-Seok JeonSchool of Mechanical Engineering, College of Engineering, Korea University, Anam-Dong, Seongbuk-Gu, Seoul, Korea.
Kyoung-Yong ChunSchool of Mechanical Engineering, College of Engineering, Korea University, Anam-Dong, Seongbuk-Gu, Seoul, Korea.
Young-Rok KimInstitute of Life Sciences and Resources and Department of Food Science and Biotechnology, College of Life Sciences, Kyung Hee University, Yongin, Korea.
Kyeong-Beom ParkDepartment of Materials Science and Engineering, Seoul National University, Seoul, Korea.
Ki-Bum KimDepartment of Materials Science and Engineering, Seoul National University, Seoul, Korea.
Chang-Soo HanSchool of Mechanical Engineering, College of Engineering, Korea University, Anam-Dong, Seongbuk-Gu, Seoul, Korea.ORCID 0000-0002-1927-9422
Korea University · KRSeoul National University · KRKyung Hee University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a novel low-noise nanopore device employing a polymer substrate. The Si substrate of a fabricated Si-substrate-based silicon nitride (Si3N4) membrane was replaced with a polymer substrate. As such, laser machining was used to make a micro-size hole through the polyimide (PI) substrate, and a thin Si3N4 membrane was then transferred onto the PI substrate. Finally, a nanopore was formed in the membrane using a transmission electron microscope for detection of biomolecules. Compared to the Si-substrate-based device, the dielectric noise was greatly reduced and the root-mean-square noise level was decreased from 146.7 to 5.4 pA. Using this device, the translocation of double-strand deoxyribonucleic acid (DNA) was detected with a high signal/noise (S/N) ratio. This type of device is anticipated to be available for future versatile sequencing technologies.

Indexed as

NanoporesDNAIonsLightMembranes, ArtificialMicroscopy, Electron, TransmissionNanotechnologyPolymersSignal-To-Noise RatioSiliconSilicon CompoundsDNAIonsMembranes, ArtificialPolymersSiliconSilicon Compoundssilicon nitride

Identifiers

PMID30028848
PMCPMC6054398
OpenAlexW2884122799

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.