Evidence map›Paper›PMID 30028675›Full record

ArticleeLife2018

Impaired spatial memory codes in a mouse model of Rett syndrome.

Sara E Kee, Xiang Mou, Huda Y Zoghbi, Daoyun Ji

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
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  15. Interneuron deficits in neurodevelopmental disorders: Implications for disease pathology and interneuron-based therapies.European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2020
    Review
  16. The role of MeCP2 in learning and memory.Learning & memory (Cold Spring Harbor, N.Y.) · 2019
    Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sara E KeeDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, United States.
Xiang MouDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, United States.ORCID 0000-0002-8579-7316
Huda Y ZoghbiDepartment of Neuroscience, Baylor College of Medicine, Houston, United States.ORCID 0000-0002-0700-3349
Daoyun JiDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, United States.ORCID 0000-0003-4115-5888
Baylor College of Medicine · USHoward Hughes Medical Institute · US

Funding

Steps towards a paternal gene activation therapy for Angelman syndromeU54HD083092 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI NELSON, DAVID LOREN, NEUL, JEFFREY L · 2014 to 2019
$7.8M
MOLECULAR PATHOGENESIS STUDIES OF RETT SYNDROMER01NS057819 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI ZOGHBI, HUDA Y · 2006 to 2025
$7.5M
Howard Hughes Medical InstituteIntellectual and Developmental Disabilities Research Center 1U54HD083092NICHD NIH HHS U54 HD083092NIH HHS 5R01NS057819NINDS NIH HHS R01 NS057819Simons Foundation 273886
6 · The paper itself

Abstract

The

Indexed as

Disease Models, AnimalAnimalsBehavior, AnimalFemaleMaleMemory DisordersMethyl-CpG-Binding Protein 2MiceMice, KnockoutNeuronal PlasticityPhenotypeRett SyndromeSpatial MemoryMecp2 protein, mouseMethyl-CpG-Binding Protein 2hippocampuslearning and memorymemory consolidationmouseneuroscienceplace cellsRett syndromeripples

Identifiers

PMID30028675
PMCPMC6054527
OpenAlexW2883378741

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.