Evidence map›Paper›PMID 30027805›Full record

ArticleThe Journal of international medical research2018

Pathogenic bacterial profile and drug resistance analysis of community-acquired pneumonia in older outpatients with fever.

Ying Luan, Yuling Sun, Shuhong Duan, Ping Zhao, Zhongying Bao

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Global Antimicrobial Non-Susceptibility Patterns ofInfection and drug resistance · 2026
    Review
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Disparate effects of methicillin-resistantThe Journal of international medical research · 2020
    Article
  14. Article
  15. Risk Factors of Multidrug-Resistant Bacteria in Lower Respiratory Tract Infections: A Systematic Review and Meta-Analysis.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2020
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ying Luan1 Department of Infectious Diseases, Beijing Shijitan Hospital, Capital Medical University, Haidian District, Beijing, China.
Yuling Sun1 Department of Infectious Diseases, Beijing Shijitan Hospital, Capital Medical University, Haidian District, Beijing, China.
Shuhong Duan1 Department of Infectious Diseases, Beijing Shijitan Hospital, Capital Medical University, Haidian District, Beijing, China.
Ping Zhao2 Department of Clinical Laboratory, Beijing Shijitan Hospital, Capital Medical University; Beijing Key Laboratory of Urinary Cellular Molecular Diagnostics, Haidian District, Beijing, China.
Zhongying Bao1 Department of Infectious Diseases, Beijing Shijitan Hospital, Capital Medical University, Haidian District, Beijing, China.
Capital Medical University · CNBeijing Shijitan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo study the pathogenic bacterial profile and drug resistance in older patients with community-acquired pneumonia (CAP) in outpatients with fever, and provide evidence to diagnose and treat CAP timely and accurately.

methodsWe studied older (>60 years) patients with CAP in Beijing Shijitan Hospital from 2016 to 2017. Pathogenic bacteria from sputum of patients were isolated and identified and their resistance to antibiotics was tested. Risk factors for multidrug-resistant CAP (MDR-CAP) and clinical outcomes were analyzed.

resultsA total of 5563 outpatients with fever were recruited and 391 had CAP. A total of 117 isolates of pathogenic bacteria were obtained from 176 CAP cases. The main pathogenic bacteria were Klebsiella pneumoniae (27.4%), Escherichia coli (17.9%), Staphylococcus aureus (12.0%), Pseudomonas aeruginosa (10.3%), and Streptococcus pneumoniae (9.4%). A drug sensitivity test (DST) showed that K. pneumoniae, E. coli, and P. aeruginosa had good sensitivity to imipenem, cefoperazone/sulbactam, piperacillin/tazobactam, and amikacin. Staphylococcus aureus and Streptococcus pneumoniae had strong sensitivity to vancomycin, linezolid, and levofloxacin. Previous multiple antibiotic treatment was an independent risk factor for MDR-CAP.

conclusionsGram-negative bacteria are the main pathogenic bacteria in older patients with CAP. Identification and DSTs of pathogens could enable accurate diagnosis and treatment of CAP.

Indexed as

Drug Resistance, Multiple, BacterialOutpatientsAgedCommunity-Acquired InfectionsFemaleFeverHumansMaleMicrobial Sensitivity TestsMiddle AgedMultivariate AnalysisPneumoniaRisk FactorsTreatment OutcomeantibioticsCommunity-acquired pneumoniadrug sensitivityinfectionolder peoplepathogenic bacteria

Identifiers

PMID30027805
PMCPMC6259400
OpenAlexW2884031001

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.