Evidence map›Paper›PMID 30027592›Full record

ReviewSeminars in dialysis2018

Dialysate potassium concentration: Should mass balance trump electrophysiology?

Patrick H Pun

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in dialysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Patrick H PunDivision of Nephrology, Department of Medicine, Duke University School of Medicine, Durham, NC, USA.
Duke University · US

Funding

Randomized trials using point of care-guided manipulation of dialysate potassium, dialysate bicarbonate, and ultrafiltration rate to prevent hemodilaysis-associated arrythmiaR34HL140477 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CHARYTAN, DAVID M, PUN, PATRICK H · 2018 to 2019
$762k
Risk Factors for Sudden Cardiac Death in Patients with Chronic Kidney DiseaseK23DK098281 · NIDDK · DUKE UNIVERSITY · PI PUN, PATRICK H · 2014 to 2016
$439k
Evaluating and Improving Cardiac Arrest Resuscitation Efforts in Hemodialysis ClinicsR03DK113324 · NIDDK · DUKE UNIVERSITY · PI PUN, PATRICK H · 2017 to 2018
$159k
NHLBI NIH HHS R34 HL140477NIDDK NIH HHS K23 DK098281NIDDK NIH HHS R03 DK113324
6 · The paper itself

Abstract

Nephrologists are faced with a difficult dilemma in choosing the ideal dialysis prescription to maintain neutral potassium mass balance. Should potassium mass balance goals prioritize the normalization of serum potassium levels using low potassium dialysate at the expense of provoking intradialytic arrhythmias, or should mass balance goals favor permissive hyperkalemia using higher dialysate potassium to avoid rapid intradialytic fluxes at the risk of more interdialytic arrhythmias? This review examines the factors that determine potassium mass balance among HD patients, the relationships between serum and dialysate potassium levels and outcomes, and concludes by examining currently available approaches to reducing risk of arrhythmias while managing potassium mass balance.

Indexed as

Arrhythmias, CardiacElectrophysiologyHemodialysis SolutionsHumansKidney Failure, ChronicPotassiumRenal DialysisRisk FactorsHemodialysis SolutionsPotassiumchronic hemodialysisclinical epidemiologyelectrolytesend-stage kidney disease

Identifiers

PMID30027592
PMCPMC6218301
OpenAlexW2884534206

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.