Evidence map›Paper›PMID 30027471›Full record

ReviewLung2018

Recurrent Pulmonary Embolism and Hypersensitivity Pneumonitis Secondary to Aspergillus, in a Compost Plant Worker: Case Report and Review of Literature.

Amos Lal, Jamal Akhtar, Soniya Pinto, Himmat Grewal, Kevin Martin

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Lung, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Dasatinib induced pleuro-pericardial effusion.Acta bio-medica : Atenei Parmensis · 2020
    Article
  9. Chronic respiratory disease
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Amos LalDepartment of Medicine, Saint Vincent Hospital, 123 Summer Street, Worcester, MA, 01608, USA. Amos.Lal@stvincenthospital.com.ORCID http://orcid.org/0000-0002-0021-2033
Jamal AkhtarDepartment of Medicine, Saint Vincent Hospital, 123 Summer Street, Worcester, MA, 01608, USA.
Soniya PintoDepartment of Radiology, Saint Vincent Hospital, 123 Summer Street, Worcester, MA, 01608, USA.
Himmat GrewalDepartment of Medicine, Saint Vincent Hospital, 123 Summer Street, Worcester, MA, 01608, USA.
Kevin MartinDivision of Pulmonology and Critical Care Medicine, Reliant Medical Group, 123 Summer Street, Worcester, MA, 01608, USA.
Saint Vincent Hospital · USReliant Medical Group · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Activation of blood coagulation pathways as a component of an allergic response has been studied in animal models. In patients with allergic diseases, clot qualities have been noted to be different in terms of denser fibrin clot with reduced plasmin-mediated clot lysis. Correlation between occupational hypersensitivity pneumonitis (HP) with thromboembolic events is scarce in the general patient population. We present a case of a 52-year-old man with recurrent venous thromboembolism with HP secondary to bioaerosol exposure in a compost plant. Biochemical evaluation found no evidence of underlying hypercoagulable state, with only remarkable findings of elevated levels of total serum immunoglobulin E and raised Aspergillus sp. IgG antibodies. The patient decided to change his working environment to one without exposure to compost or other fungal elements. His symptoms and pulmonary function tests gradually improved without any subsequent intervention. The patient chose against the advice of his care providers to discontinue warfarin anti-coagulation that had been recommended for lifelong duration after recurrent pulmonary thromboembolism. At a 4-year follow-up he has remained free of any further episodes of venous thromboembolic events without any anti-coagulation. Repeated imaging studies after cessation of exposure demonstrated clearance of multiple lung nodules and improvement in DLco.

Indexed as

CompostingAlveolitis, Extrinsic AllergicAspergillusForced Expiratory VolumeHumansImmunoglobulin EImmunoglobulin GInhalation ExposureMaleMiddle AgedOccupational DiseasesPulmonary EmbolismRecovery of FunctionRecurrenceVenous ThromboembolismVital CapacityImmunoglobulin EImmunoglobulin GAspergillusComputed tomographyHypersensitivity pneumonitisPulmonary embolismPulmonary function tests

Identifiers

PMID30027471
OpenAlexW2884985215

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.