Evidence map›Paper›PMID 30027445›Full record

ArticleHernia : the journal of hernias and abdominal wall surgery2018

Mesh-augmented versus direct abdominal closure in patients undergoing open abdomen treatment.

M O Jakob, C Schwarz, T Haltmeier, J Zindel, T Pinworasarn, D Candinas, P Starlinger, G Beldi

Open access · hybridAbstract readComparative StudyMulticenter Study
In one paragraph

Article in Hernia : the journal of hernias and abdominal wall surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Dynamic closure techniques for treatment of an open abdomen: an update.Hernia : the journal of hernias and abdominal wall surgery · 2020
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Observational
  6. Open abdomen in the trauma ICU patient: who? when? why? and what are the outcome results?European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

M O JakobDepartment of Visceral Surgery and Medicine, University Hospital, Bern, Switzerland.
C SchwarzDepartment of Surgery, General Hospital, Medical University of Vienna, Vienna, Austria.
T HaltmeierDepartment of Visceral Surgery and Medicine, University Hospital, Bern, Switzerland.
J ZindelDepartment of Visceral Surgery and Medicine, University Hospital, Bern, Switzerland.
T PinworasarnDepartment of Visceral Surgery and Medicine, University Hospital, Bern, Switzerland.
D CandinasDepartment of Visceral Surgery and Medicine, University Hospital, Bern, Switzerland.
P StarlingerDepartment of Surgery, General Hospital, Medical University of Vienna, Vienna, Austria.
G BeldiDepartment of Visceral Surgery and Medicine, University Hospital, Bern, Switzerland. guido.beldi@insel.ch.
University Hospital of Bern · CHVienna General Hospital · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOpen abdomen (OA) may be required in patients with abdominal trauma, sepsis or compartment syndrome. Vacuum-assisted wound closure and mesh-mediated fascial traction (VAWCM) is a widely used approach for temporary abdominal closure to close the abdominal wall. However, this method is associated with a high incidence of re-operations in short term and late sequelae such as incisional hernia. The current study aims to compare the results of surgical strategies of OA with versus without permanent mesh augmentation.

methodsPatients with OA treatment undergoing vacuum-assisted wound closure and an intraperitoneal onlay mesh (VAC-IPOM) implantation were compared to VAWCM with direct fascial closure which represents the current standard of care. Outcomes of patients from two tertiary referral centers that performed the different strategies for abdominal closure after OA treatment were compared in univariate and multivariate regression analysis.

resultsA total of 139 patients were included in the study. Of these, 50 (36.0%) patients underwent VAC-IPOM and 89 (64.0%) patients VAWCM. VAC-IPOM was associated with reduced re-operations (adjusted incidence risk ratio 0.48 per 10-person days; CI 95% = 0.39-0.58, p < 0.001), reduced duration of stay on intensive care unit (ICU) [adjusted hazard ratio (aHR) 0.53; CI 95% = 0.36-0.79, p = 0.002] and reduced hospital stay (aHR 0.61; CI 95% = 0.040-0.94; p = 0.024). In-hospital mortality [22.5 vs 18.0%, risk difference - 4.5; confidence interval (CI) 95% = - 18.2 to 9.3; p = 0.665] and the incidence of intestinal fistula (18.0 vs 22.0%, risk difference 4.0; CI 95% = -10.0 to 18.0; p = 0.656) did not differ between the two groups. In Kaplan-Meier analysis, hernia-free survival was significantly increased after VAC-IPOM (p = 0.041).

conclusionsIn patients undergoing OA treatment, intraperitoneal mesh augmentation is associated with a significantly decreased number of re-operations, duration of hospital and ICU stay and incidence of incisional hernias when compared to VAWCM.

Indexed as

Abdominal Wound Closure TechniquesSurgical MeshAbdominal WallAgedFasciotomyFemaleHumansIncisional HerniaLength of StayMaleMiddle AgedNegative-Pressure Wound TherapyReoperationMesh augmentationNon-absorbable meshOpen abdomenVacuum-assisted wound closure and mesh-mediated fascial traction

Identifiers

PMID30027445
PMCPMC6153946
OpenAlexW2883356241

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.