Evidence map›Paper›PMID 30027380›Full record

ArticleJournal of nephrology2018

The pregnancy outcomes in patients with stage 3-4 chronic kidney disease and the effects of pregnancy in the long-term kidney function.

Yingdong He, Jing Liu, Qingqing Cai, Jicheng Lv, Feng Yu, Qian Chen, Minghui Zhao

Abstract readComparative Study
In one paragraph

Article in Journal of nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Kidney disease and reproductive health.Nature reviews. Nephrology · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. The impact of chronic kidney disease Stages 3-5 on pregnancy outcomes.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2021
    Article
  9. Article
  10. Prepregnancy renal function and risk of preterm birth and related outcomes.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2020
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yingdong HeDepartment of Obstetrics and Gynecology, Peking University, First Hospital, Beijing, 100034, People's Republic of China.
Jing LiuDepartment of Obstetrics and Gynecology, Peking University, First Hospital, Beijing, 100034, People's Republic of China.
Qingqing CaiRenal Division, Department of Medicine, Peking University, First Hospital, Peking University Institute of Nephrology, Beijing, People's Republic of China.
Jicheng LvRenal Division, Department of Medicine, Peking University, First Hospital, Peking University Institute of Nephrology, Beijing, People's Republic of China.
Feng YuRenal Division, Department of Medicine, Peking University, First Hospital, Peking University Institute of Nephrology, Beijing, People's Republic of China.
Qian ChenDepartment of Obstetrics and Gynecology, Peking University, First Hospital, Beijing, 100034, People's Republic of China. chenqianobs@126.com.ORCID http://orcid.org/0000-0003-2508-4311
Minghui ZhaoRenal Division, Department of Medicine, Peking University, First Hospital, Peking University Institute of Nephrology, Beijing, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the pregnancy outcomes for patients with stage 3-4 chronic kidney disease (CKD) and the effects of pregnancy on kidney function.

methodsClinical data of pregnant women with CKD in the Peking University First Hospital between January 1st 2005 and October 1st 2016 were retrospectively analysed. The pregnancy outcomes of patients with different stages of CKD were compared. Patients with stage 3-4 CKD were followed up by telephone interview, and non-pregnant patients with stage 3-4 CKD were selected using the propensity score method to analyse the effects of pregnancy on kidney function.

resultsA total of 293 women with 300 pregnancies met the study criteria. There were 30 cases of stage 3-4 CKD. The incidence of adverse pregnancy outcomes of patients with stage 3-4 CKD was significantly higher than that with stage 1 CKD. The mean postpartum follow-up time of pregnant patients with CKD was 49.0 ± 33.1 months. A total of 26 cases of stage 3-4 CKD were followed up. During the follow-up period, 8 patients progressed to ESRD. A total of 28 non-pregnant patients with stage 3-4 CKD were selected as the control group. The results of multivariate analysis revealed that pregnancy did not increase the risk of deterioration of kidney function.

conclusionPatients with stage 3-4 CKD in early pregnancy had a significantly increased risk of adverse pregnancy outcomes. Pregnancy itself did not seem to accelerate kidney disease progression in patients with stage 3-4 CKD.

Indexed as

AdultArterial PressureChinaDisease ProgressionFemaleGlomerular Filtration RateHumansIncidenceKidneyKidney Failure, ChronicPregnancyPregnancy ComplicationsPregnancy OutcomePrognosisRenal Insufficiency, ChronicRetrospective StudiesChronic kidney diseasePregnancyRenal disease progression

Identifiers

PMID30027380
PMCPMC6244551

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.