ArticlePediatric radiology2018
A retrospective segmentation analysis of placental volume by magnetic resonance imaging from first trimester to term gestation.
Article in Pediatric radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- MDIFN: a deep learning-based multi-dimensional interaction fusion network for placental MRI segmentation.Quantitative imaging in medicine and surgery · 2026Article
- Charting normative reference values and Z-scores for MRI-derived in vivo placental growth.Pediatric radiology · 2026Observational
- The placental maturation inflection point: an integrative biological framework for understanding early-onset versus late-onset preeclampsia.Frontiers in endocrinology · 2026Review
- Article
- Placental and Fetal Brain Volumes in Congenital Heart Disease Are Smallest Among Fetuses With Genetic Abnormalities.Prenatal diagnosis · 2025Article
- Placental size and umbilical vein volume blood flow.Acta obstetricia et gynecologica Scandinavica · 2025Article
- Consistency Regularization Improves Placenta Segmentation in Fetal EPI MRI Time Series.Perinatal, preterm and paediatric image analysis (2025) · 2025Article
- Placental T2* as a measure of placental function across field strength from 0.55T to 3T.Scientific reports · 2024Article
- Interdependence of placenta and fetal cardiac development.Prenatal diagnosis · 2024Review
- Placental size at gestational week 36: Comparisons between ongoing pregnancies and deliveries.Acta obstetricia et gynecologica Scandinavica · 2024Article
- Placental volume in pregnant women with opioid use: prenatal MRI assessment.The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2023Article
- Fetal Growth Restriction Is Associated with Pregnancy Associated Plasma Protein A and Uterine Artery Doppler in First Trimester.Journal of clinical medicine · 2023Article
- Placenta segmentation in ultrasound imaging: Addressing sources of uncertainty and limited field-of-view.Medical image analysis · 2023Article
- Placental vascular malperfusion lesions in fetal congenital heart disease.American journal of obstetrics and gynecology · 2022Article
- Standard diffusion-weighted, diffusion kurtosis and intravoxel incoherent motion MR imaging of the whole placenta: a pilot study of volumetric analysis.Annals of translational medicine · 2022Article
- Neuroplacentology in congenital heart disease: placental connections to neurodevelopmental outcomes.Pediatric research · 2022Review
- Fetal origin of brain dysmaturation in congenital heart disease - Challenges and opportunities for interventions.Journal of neonatal-perinatal medicine · 2022Article
- Placental pathologic lesions associated with stroke in term neonates.Frontiers in endocrinology · 2022Article
- Normative placental structure in pregnancy using quantitative Magnetic Resonance Imaging.Placenta · 2021Observational
- Placental origins of neonatal diseases: toward a precision medicine approach.Pediatric research · 2021Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
backgroundAbnormalities of the placenta affect 5-7% of pregnancies. Because disturbances in fetal growth are often preceded by dysfunction of the placenta or attenuation of its normal expansion, placental health warrants careful surveillance. There are limited normative data available for placental volume by MRI.
objectiveTo determine normative ranges of placental volume by MRI throughout gestation. MATERIALS AND
methodsIn this cross-sectional retrospective analysis, we reviewed MRI examinations of pregnant females obtained between 2002 and 2017 at a single institution. We performed semi-automated segmentation of the placenta in images obtained in patients with no radiologic evidence of maternal or fetal pathology, using the Philips Intellispace Tumor Tracking Tool.
resultsPlacental segmentation was performed in 112 women and had a high degree of interrater reliability (single-measure intraclass correlation coefficient =0.978 with 95% confidence interval [CI] 0.956, 0.989; P<0.001). Normative data on placental volume by MRI increased nonlinearly from 6 weeks to 39 weeks of gestation, with wider variability of placental volume at higher gestational age (GA). We fit placental volumetric data to a polynomial curve of third order described as placental volume = -0.02*GA
conclusionThis study provides normative placental volume by MRI from early first trimester to term gestation. Deviations in placental volume from normal might prove to be an imaging biomarker of adverse fetal health and neonatal outcome, and further studies are needed to more fully understand this metric. Assessment of placental volume should be considered in all routine fetal MRI examinations.
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