Evidence map›Paper›PMID 30027346›Full record

ArticlePflugers Archiv : European journal of physiology2018

The renal vasodilatory effect of prostaglandins is ameliorated in isolated-perfused kidneys of endotoxemic mice.

Manuel Meurer, Katharina Ebert, Frank Schweda, Klaus Höcherl

Abstract read
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In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Manuel MeurerInstitute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Fahrstr. 17, 91054, Erlangen, Germany.
Katharina EbertInstitut für Prophylaxe und Epidemiologie der Kreislaufkrankheiten, Poliklinik, Klinikum der Universität München, Ludwig-Maximilians-Universität München, Munich, Germany.
Frank SchwedaInstitute of Physiology, University of Regensburg, Regensburg, Germany.
Klaus HöcherlInstitute of Experimental and Clinical Pharmacology and Toxicology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Fahrstr. 17, 91054, Erlangen, Germany. klaus.hoecherl@fau.de.ORCID 0000-0001-7278-0702
Friedrich-Alexander-Universität Erlangen-Nürnberg · DELudwig-Maximilians-Universität München · DEUniversity of Regensburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endotoxemia-related acute kidney injury (AKI) is associated with increased formation of prostaglandins, which may serve as a compensatory mechanism to maintain renal function. We hypothesized that an increase of renal EP

Indexed as

VasodilationAcute Kidney InjuryAnimalsEndotoxemiaKidneyMaleMiceMice, Inbred C57BLProstaglandinsReceptors, ProstaglandinReninRNA, MessengerVasodilator AgentsProstaglandinsReceptors, ProstaglandinReninRNA, MessengerVasodilator AgentsCyclooxygenaseEndotoxemiaProstacyclinProstaglandinRenal vascular toneRenin

Identifiers

PMID30027346
OpenAlexW2883302260

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.