ArticleNeuroradiology2018
Schizencephaly revisited.
Article in Neuroradiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 84 citations in OpenAlex.
- Foetal disruptive brain injuries: Diagnosing the underlying pathogenetic mechanisms with cranial ultrasonography.Developmental medicine and child neurology · 2025Review
- Fetal malformations of cortical development: review and clinical guidance.Brain : a journal of neurology · 2025Review
- Open Lip Schizencephaly Misdiagnosed as Paralytic Poliomyelitis in an 85-Year-Old: A Case Report.Clinical case reports · 2025Article
- Two-stage surgical intervention for a rare case of intersected nasoethmoidal encephalocele and open-lip schizencephaly in an infant: illustrative case.Journal of neurosurgery. Case lessons · 2024Article
- Open lip schizencephaly: An unusual cause of hemiparesis: A case report.Radiology case reports · 2024Article
- [Congenital malformations of the brain misinterpreted as sequelae of poliomyelitis].Zeitschrift fur Gerontologie und Geriatrie · 2024Article
- A case of closedlip schizencephaly with absent septum pellucidum in an adult presenting with seizure disorder.Clinical case reports · 2023Article
- Schizencephaly in Hereditary Hemorrhagic Telangiectasia.AJNR. American journal of neuroradiology · 2022Article
- Bilateral open lip schizencephaly.Annals of medicine and surgery (2012) · 2022Article
- Traumatic epidural hematoma in a patient with severe schizencephaly.Clinical case reports · 2021Article
- Narrative review of epilepsy: getting the most out of your neuroimaging.Translational pediatrics · 2021Review
- Motor Organization in Schizencephaly: Outcomes of Transcranial Magnetic Stimulation and Diffusion Tensor Imaging of Motor Tract Projections Correlate with the Different Domains of Hand Function.BioMed research international · 2021Article
- Congenital Visual Field Loss from a Schizencephalic Cleft Damaging Meyer's Loop.Neuro-ophthalmology (Aeolus Press) · 2021Article
- Definitions and classification of malformations of cortical development: practical guidelines.Brain : a journal of neurology · 2020Review
- Persistent falcine sinus with temporo-occipital schizencephaly: case report with a review of literature in relation to the undeveloped vein of Galen and/or straight sinus.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Review
- 2018/2019.Neuroradiology · 2019Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIn this paper, I will report the range of appearances of schizencephaly in children and fetuses by reviewing a 10-year experience from a single centre and detail classification systems for the different forms of schizencephaly. This will lead to re-assessment of possible aetiological and mechanistic causes of schizencephaly.
methodsAll cases of pediatric and fetal schizencephaly were located on the local database between 2007 and 2016 inclusive. The studies were reviewed for the presence, location and type of schizencephaly, as well as the state of the (cavum) septum pellucidum, the location of the fornices and the presence of other brain abnormalities.
resultsThe review included 21 children and 11 fetuses with schizencephaly. Schizencephaly (type 1) was found in 9% of children but no fetuses, schizencephaly (type 2) was present in 67% of the pediatric cases and in 45% of fetuses, whilst schizencephaly (type 3) was present in approximately 24% of children and 55% of fetuses. Other brain abnormalities were found in 67% of children and 55% of fetuses.
conclusionI have proposed a new system for classifying schizencephaly that takes into account all definitions of the abnormality in the literature. Using that approach, I have described the appearances and associations of pediatric and fetal cases of schizencephaly from a single centre. Review of the current literature appears to favour an acquired destructive aetiology for most cases of schizencephaly, and I have proposed a mechanism to explain the cortical formation abnormalities found consistently in and around areas of schizencephaly.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.