Evidence map›Paper›PMID 30027067›Full record

ArticleAnesthesiology and pain medicine2018

Occlusion of the Ascenda Catheter in a Patient with Pump Twiddler's Sydrome: A Case Report.

Jianning Shao, Leonardo Frizon, Andre G Machado, Keith McKee, Francois Bethoux, Jennifer Hartman, Sean J Nagel

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Anesthesiology and pain medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Flipping the script: Conservative management of a flipped intrathecal baclofen pump.PM & R : the journal of injury, function, and rehabilitation · 2025
    Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jianning ShaoCleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH.
Leonardo FrizonCenter for Neurological Restoration, Cleveland Clinic, Cleveland, Ohio.
Andre G MachadoCenter for Neurological Restoration, Cleveland Clinic, Cleveland, Ohio.
Keith McKeeMellen Center, Cleveland Clinic, Cleveland, OH.
Francois BethouxMellen Center, Cleveland Clinic, Cleveland, OH.
Jennifer HartmanMellen Center, Cleveland Clinic, Cleveland, OH.
Sean J NagelCenter for Neurological Restoration, Cleveland Clinic, Cleveland, Ohio.
Cleveland Clinic · USCase Western Reserve University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIntrathecal baclofen (ITB) therapy is an effective way to manage spasticity in numerous conditions, including multiple sclerosis, stroke, and cerebral palsy. While pump failure is a common complication of ITB, improvements in device design have led to reduction of complications. In particular, the Ascenda catheter from Medtronic, Inc. was designed to resist kinking and associated complications; indeed, no incidences of catheter twisting or occlusion have been reported in literature prior to this case. CASE REPORT: We report a case of a 32-year old gentleman who presented to the clinic with symptoms of baclofen withdrawal 19 months after he had a programmable pump implanted for spasticity. During the diagnostic evaluation it was discovered that the patients pump had flipped in his abdominal pocket. He was taken to surgery to reorient the pump, during which time it was noted the catheter was tightly coiled on itself occluding flow. The twisted catheter was excised and replaced with a new segment.His symptoms subsequently resolved.

conclusionsAlthough catheter occlusions have subsided since the approval of the Ascenda catheter, pump twiddler's syndrome remains a risk factor for this complication. This is the first report describing this syndrome in a patient with the Ascenda catheter.

Indexed as

Ascenda CatheterBaclofen, Twiddler’s SyndromeIntrathecal Baclofen Therapy (ITB)

Identifiers

PMID30027067
PMCPMC6045776
OpenAlexW2800752908

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.