Evidence map›Paper›PMID 30027059›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2018

A Metal Chelator as a Plasmonic Signal-Generation Superregulator for Ultrasensitive Colorimetric Bioassays of Disease Biomarkers.

Qian Zhao, Jiafang Piao, Weipan Peng, Jun Wang, Weichen Gao, Xiaoli Wu, Hanjie Wang, Xiaoqun Gong, Jin Chang, Bingbo Zhang

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Review
  3. Nanotechnology for the Diagnosis and Treatment of Liver Cancer.International journal of nanomedicine · 2024
    Review
  4. Ultrasensitive Detection of Biomarkers in a Color-Switchable Microcavity-Reactor Laser.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Article
  5. Applications of nanotechnology in virus detection, tracking, and infection mechanisms.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2021
    Review
  6. Silica-Based Nanoframeworks Involved Hepatocellular Carcinoma Theranostic.Frontiers in bioengineering and biotechnology · 2021
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Qian ZhaoSchool of Life Sciences Tianjin Engineering Center of Micro-Nano Biomaterials and Detection-Treatment Technology Tianjin University Tianjin 300072 China.
Jiafang PiaoSchool of Life Sciences Tianjin Engineering Center of Micro-Nano Biomaterials and Detection-Treatment Technology Tianjin University Tianjin 300072 China.
Weipan PengSchool of Life Sciences Tianjin Engineering Center of Micro-Nano Biomaterials and Detection-Treatment Technology Tianjin University Tianjin 300072 China.
Jun WangInstitute of Photomedicine Shanghai Skin Disease Hospital The Institute for Biomedical Engineering and Nano Science Tongji University School of Medicine Shanghai 200443 China.
Weichen GaoSchool of Life Sciences Tianjin Engineering Center of Micro-Nano Biomaterials and Detection-Treatment Technology Tianjin University Tianjin 300072 China.
Xiaoli WuSchool of Life Sciences Tianjin Engineering Center of Micro-Nano Biomaterials and Detection-Treatment Technology Tianjin University Tianjin 300072 China.
Hanjie WangSchool of Life Sciences Tianjin Engineering Center of Micro-Nano Biomaterials and Detection-Treatment Technology Tianjin University Tianjin 300072 China.
Xiaoqun GongSchool of Life Sciences Tianjin Engineering Center of Micro-Nano Biomaterials and Detection-Treatment Technology Tianjin University Tianjin 300072 China.
Jin ChangSchool of Life Sciences Tianjin Engineering Center of Micro-Nano Biomaterials and Detection-Treatment Technology Tianjin University Tianjin 300072 China.
Bingbo ZhangInstitute of Photomedicine Shanghai Skin Disease Hospital The Institute for Biomedical Engineering and Nano Science Tongji University School of Medicine Shanghai 200443 China.
Tianjin University · CNTongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enzyme-based assays have been widely applied in clinical diagnosis for decades. However, the intrinsic limitations of enzymes, such as low operation stability, mediocre sensitivity, and high cost in production and purification, heavily constrain their detection application. Here, an enzyme-free assay is reported that relies on the strong chelating capability of ethylenediamine tetraacetic acid disodium salt (EDTA•2Na, the chelator) for Au

Indexed as

chelating capabilityenzyme‐based assaysethylenediamine tetraacetic acid disodium saltoperation stabilitysignal generation

Identifiers

PMID30027059
PMCPMC6051378
OpenAlexW2804193538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.