Evidence map›Paper›PMID 30026940›Full record

ArticleAntimicrobial resistance and infection control2018

Antibiotic use on paediatric inpatients in a teaching hospital in the Gambia, a retrospective study.

Pa Saidou Chaw, Kristin Maria Schlinkmann, Heike Raupach-Rosin, André Karch, Mathias W Pletz, Johannes Huebner, Ousman Nyan, Rafael Mikolajczyk

Abstract read
In one paragraph

Article in Antimicrobial resistance and infection control, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pa Saidou Chaw1PhD Programme, Epidemiology"Braunschweig-Hannover, Department of Epidemiology, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany.
Kristin Maria Schlinkmann1PhD Programme, Epidemiology"Braunschweig-Hannover, Department of Epidemiology, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany.
Heike Raupach-Rosin3Department of Epidemiology, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany.
André Karch1PhD Programme, Epidemiology"Braunschweig-Hannover, Department of Epidemiology, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany.
Mathias W Pletz5Center for Infectious Diseases and Infection Control, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany.
Johannes Huebner6Division of Paediatric Infectious Diseases, Dr. Von Hauner Children's Hospital, Ludwig Maximilian University Munich, 80337 Munich, Germany.
Ousman NyanDepartment of Medicine, School of Medicine and Allied Health Sciences, University of the Gambia, Edward Francis Small Teaching Hospital, Banjul, The Gambia.
Rafael Mikolajczyk2Institute for Medical Epidemiology, Biometry, and Informatics (IMEBI), Medical Faculty of the Martin-Luther University Halle-Wittenberg, 06112 Halle (Saale), Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Antibiotics are useful but increasing resistance is a major problem. Our objectives were to assess antibiotic use and microbiology testing in hospitalized children in the Gambia. Methods: We conducted a retrospective analysis of paediatric inpatient data at The Edward Francis Small Teaching Hospital in Banjul, The Gambia. We extracted relevant data from the admission folders of all patients (aged > 28 days to 15 years) admitted in 2015 (January-December), who received at least one antibiotic for 24 h. We also reviewed the microbiology laboratory record book to obtain separate data for the bacterial isolates and resistance test results of all the paediatric inpatients during the study period. Results: Over half of the admitted patients received at least one antibiotic during admission (496/917) with a total consumption of 670.7 Days of Antibiotic Therapy/1000 Patient-Days. The clinical diagnoses included an infectious disease for 398/496, 80.2% of the patients on antibiotics, pneumonia being the most common (184/496, 37.1%). There were 51 clinically relevant bacterial isolates, Conclusions: More than half of the admitted patients received antibiotics. The reported antibiotic resistance was highest to the most commonly used antibiotics such as ampicillin. Efforts to maximize definitive antibiotic indication such as microbiological testing prior to start of antibiotics should be encouraged where possible for a more rational antibiotic use.

Indexed as

AdolescentAnti-Bacterial AgentsBacteriaBacterial InfectionsChildChild, PreschoolFemaleGambiaHospitals, TeachingHumansInfantInpatientsMalePediatricsRetrospective StudiesAnti-Bacterial AgentsAntibiotic resistanceAntibiotic stewardshipAntibiotic useMicrobiologyPaediatrics

Identifiers

PMID30026940
PMCPMC6048718

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.