Evidence map›Paper›PMID 30026919›Full record

ReviewF1000Research2018

Recent advances in understanding and managing acute pancreatitis.

Amar Mandalia, Erik-Jan Wamsteker, Matthew J DiMagno

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in F1000Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04647097 (Recurrent Acute Pancreatitis Prevention by the Elimination of Alcohol and Cigarette Smoking), which is not on this map. Cited by 33 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 4 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04647097 narecruitingnot on this mapstarted 2022, after this paper: background citation

Recurrent Acute Pancreatitis Prevention by the Elimination of Alcohol and Cigarette Smoking (REAPPEAR): Protocol of a Randomized Controlled Trial and a Cohort Study

TypeinterventionalSponsorUniversity of PecsRan2022 to 2028Enrolled364ConditionsAcute Pancreatitis, Recurrent Acute PancreatitisArmsStandard intervention only, Standard intervention plus repeated intervention
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 4 syntheses or guidelines pooled it, 52 citations in OpenAlex.

  1. Pooled it
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  5. Trial
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. B Cells and Double-Negative B Cells (CD27Diseases (Basel, Switzerland) · 2024
    Article
  12. Article
  13. Heart rate variability in acute pancreatitis: a narrative review.Translational gastroenterology and hepatology · 2024
    Review
  14. Article
  15. What has changed? The impact of the COVID-19 pandemic on the management of acute biliary pancreatitis.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2023
    Article
  16. Article
  17. Article
  18. Initiation and severity of experimental pancreatitis are modified by phosphate.American journal of physiology. Gastrointestinal and liver physiology · 2022
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Amar MandaliaDivision of Gastroenterology and Hepatology, University of Michigan School of Medicine, Ann Arbor, MI, 48109, USA.
Erik-Jan WamstekerDivision of Gastroenterology and Hepatology, University of Michigan School of Medicine, Ann Arbor, MI, 48109, USA.
Matthew J DiMagnoDivision of Gastroenterology and Hepatology, University of Michigan School of Medicine, Ann Arbor, MI, 48109, USA.ORCID 0000-0003-1155-1919
University of Michigan · US

Funding

Acute Pancreatitis Alert & Decision Support Improves Care & Cuts Length of StayR21DK106647 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DIMAGNO, MATTHEW J · 2016 to 2017
$440k
NIDDK NIH HHS R21 DK106647
6 · The paper itself

Abstract

This review highlights advances made in recent years in the diagnosis and management of acute pancreatitis (AP). We focus on epidemiological, clinical, and management aspects of AP. Additionally, we discuss the role of using risk stratification tools to guide clinical decision making. The majority of patients suffer from mild AP, and only a subset develop moderately severe AP, defined as a pancreatic local complication, or severe AP, defined as persistent organ failure. In mild AP, management typically involves diagnostic evaluation and supportive care resulting usually in a short hospital length of stay (LOS). In severe AP, a multidisciplinary approach is warranted to minimize morbidity and mortality over the course of a protracted hospital LOS. Based on evidence from guideline recommendations, we discuss five treatment interventions, including intravenous fluid resuscitation, feeding, prophylactic antibiotics, probiotics, and timing of endoscopic retrograde cholangiopancreatography (ERCP) in acute biliary pancreatitis. This review also highlights the importance of preventive interventions to reduce hospital readmission or prevent pancreatitis, including alcohol and smoking cessation, same-admission cholecystectomy for acute biliary pancreatitis, and chemoprevention and fluid administration for post-ERCP pancreatitis. Our review aims to consolidate guideline recommendations and high-quality studies published in recent years to guide the management of AP and highlight areas in need of research.

Indexed as

Acute DiseaseHumansPancreatitisAcute pancreatitisalcoholcannabischolecystectomyercpfeedinggallstonesgoal directed fluid therapysmoking

Identifiers

PMID30026919
PMCPMC6039949
OpenAlexW2810969038

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.