Evidence map›Paper›PMID 30026877›Full record

ArticleTheranostics2018

Precise theranostic nanomedicines for inhibiting vulnerable atherosclerotic plaque progression through regulation of vascular smooth muscle cell phenotype switching.

Sai Ma, Seyed Mohammad Motevalli, Jiangwei Chen, Meng-Qi Xu, Yabin Wang, Jing Feng, Ya Qiu, Dong Han, Miaomiao Fan, Meiling Ding and 4 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.

  1. Extreme Diversity of the Human Vascular Mesenchymal Cell Landscape.Journal of the American Heart Association · 2020
    Pooled it
  2. Review
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  6. Article
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  8. Article
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  13. Article
  14. Relationship between nailfold capillaroscopy parameters and the severity of diabetic retinopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Nanotechnology for cardiovascular diseases.Innovation (Cambridge (Mass.)) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 1 country.

Sai MaDepartment of Cardiology & National Clinical Research Center of Geriatrics Disease, Chinese PLA General Hospital, Beijing 100853, China.
Seyed Mohammad MotevalliLaboratory of Controllable Nanopharmaceuticals, Chinese Academy of Sciences (CAS) Center for Excellence in Nanoscience and CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology of China, Beijing 100190, China.
Jiangwei ChenDepartment of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.
Meng-Qi XuDepartment of Cardiology & National Clinical Research Center of Geriatrics Disease, Chinese PLA General Hospital, Beijing 100853, China.
Yabin WangDepartment of Cardiology & National Clinical Research Center of Geriatrics Disease, Chinese PLA General Hospital, Beijing 100853, China.
Jing FengDepartment of Emergency Medicine, Jinling Hospital, Nanjing 210000, China.
Ya QiuDepartment of Cardiology & National Clinical Research Center of Geriatrics Disease, Chinese PLA General Hospital, Beijing 100853, China.
Dong HanDepartment of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.
Miaomiao FanDepartment of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.
Meiling DingState Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Disease and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an 710032, China.
Li FanDepartment of Geriatric Cardiology & National Clinical Research Center of Geriatric Disease, Chinese PLA General Hospital, Beijing 100853, China.
Weisheng GuoLaboratory of Controllable Nanopharmaceuticals, Chinese Academy of Sciences (CAS) Center for Excellence in Nanoscience and CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology of China, Beijing 100190, China.
Xing-Jie LiangLaboratory of Controllable Nanopharmaceuticals, Chinese Academy of Sciences (CAS) Center for Excellence in Nanoscience and CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology of China, Beijing 100190, China.
Feng CaoDepartment of Cardiology & National Clinical Research Center of Geriatrics Disease, Chinese PLA General Hospital, Beijing 100853, China.
Chinese PLA General Hospital · CNAir Force Medical University · CNNational Center for Nanoscience and Technology · CNXijing Hospital · CNChinese Academy of Sciences · CNJinling Institute of Technology · CNNational Clinical Research Center for Digestive Diseases · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronary heart disease is a prevalent and fatal killer caused by vulnerable atherosclerotic plaques (VASPs). However, the precise detection and treatment of VASPs remains a difficult challenge. Here, we present the development of noninvasive human serum albumin (HSA)-based theranostic nanomedicines (NMs) for the specific diagnosis and effective therapy of VASPs.

Indexed as

AnimalsDisease Models, AnimalIndocyanine GreenMiceMolecular Targeted TherapyMuscle, Smooth, VascularMyocytes, Smooth MuscleOsteopontinPeptidesPhenotypePlaque, AtheroscleroticSirtuin 1Theranostic NanomedicineIndocyanine GreenOsteopontinPeptidesSirtuin 1atherosclerosisosteopontinsirtuin 1theranostic nanomedicinesvascular smooth muscle cells

Identifiers

PMID30026877
PMCPMC6037040
OpenAlexW2808862563

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.