Evidence map›Paper›PMID 30026864›Full record

ArticleTheranostics2018

CCR2-dependent monocytes/macrophages exacerbate acute brain injury but promote functional recovery after ischemic stroke in mice.

Weirong Fang, Xuan Zhai, Dong Han, Xiaoxing Xiong, Tao Wang, Xun Zeng, Shucheng He, Rui Liu, Masaaki Miyata, Baohui Xu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

96 citing papers in PubMed, 143 citations in OpenAlex.

  1. Article
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  12. Monocyte-derived macrophages and their roles in ischemic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Review
  13. Article
  14. Article
  15. Review
  16. Injury to repair: Functions of microglia and monocyte-derived cells in ischemic stroke.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2025
    Review
  17. Review
  18. Review
  19. Article
  20. Review

36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Weirong FangDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Xuan ZhaiDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Dong HanDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Xiaoxing XiongDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Tao WangDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Xun ZengThe First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China.
Shucheng HeDepartment of Physiology, China Pharmaceutical University, Nanjing 210009, China.
Rui LiuDepartment of Physiology, China Pharmaceutical University, Nanjing 210009, China.
Masaaki MiyataDepartment of Cardiovascular Medicine and Hypertension, Graduate School of Medical and Dental Sciences, Kagoshima University, Japan.
Baohui XuDepartment of Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Heng ZhaoDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Stanford University · USChina Pharmaceutical University · CNKagoshima University · JPZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Recovery of FunctionAnimalsBrain InjuriesBrain IschemiaDisease Models, AnimalGermaniumImmunologic FactorsMacrophagesMiceMice, KnockoutMonocytesOrganometallic CompoundsPropionatesReceptors, CCR2StrokeCcr2 protein, mouseGermaniumImmunologic FactorsOrganometallic CompoundspropagermaniumPropionatesReceptors, CCR2CCR2functional recoveryischemic strokemonocytes

Identifiers

PMID30026864
PMCPMC6037034
OpenAlexW2808648467

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.