Evidence map›Paper›PMID 30026674›Full record

Trial reportContrast media & molecular imaging2018

Differential Diagnosis between Low-Grade and High-Grade Astrocytoma Using System A Amino Acid Transport PET Imaging with C-11-MeAIB: A Comparison Study with C-11-Methionine PET Imaging.

Ryuichi Nishii, Tatsuya Higashi, Shinya Kagawa, Maya Arimoto, Yoshihiko Kishibe, Masaaki Takahashi, Shigeki Yamada, Masaaki Saiki, Yoshiki Arakawa, Hiroshi Yamauchi and 9 more

Open access · hybridAbstract readClinical TrialComparative Study
In one paragraph

Trial report in Contrast media & molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. The Emerging Role of Amino Acid PET in Neuro-Oncology.Bioengineering (Basel, Switzerland) · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 6 institutions in 1 country.

Ryuichi NishiiDepartment of Molecular Imaging and Theranostics, National Institute of Radiological Sciences (NIRS), QST, 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, Japan.ORCID 0000-0002-2096-4611
Tatsuya HigashiDepartment of Molecular Imaging and Theranostics, National Institute of Radiological Sciences (NIRS), QST, 4-9-1 Anagawa, Inage-ku, Chiba 263-8555, Japan.ORCID 0000-0002-8338-4737
Shinya KagawaDivision of PET Imaging, Shiga Medical Center Research Institute, 5-4-30 Moriyama, Moriyama, Shiga 524-8524, Japan.
Maya ArimotoDepartment of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan.
Yoshihiko KishibeDivision of PET Imaging, Shiga Medical Center Research Institute, 5-4-30 Moriyama, Moriyama, Shiga 524-8524, Japan.
Masaaki TakahashiDivision of PET Imaging, Shiga Medical Center Research Institute, 5-4-30 Moriyama, Moriyama, Shiga 524-8524, Japan.
Shigeki YamadaDepartment of Neurosurgery, Rakuwakai Otowa Hospital, 2 Otowachinjicho, Yamashina-ku, Kyoto 607-8062, Japan.
Masaaki SaikiDepartment of Radiology, Japanese Red Cross Otsu Hospital, 1-1-35 Nagara, Otsu, Shiga 520-8511, Japan.
Yoshiki ArakawaDepartment of Neurosurgery, Graduate School of Medicine, Kyoto University, 54 ShogoinKawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan.
Hiroshi YamauchiDivision of PET Imaging, Shiga Medical Center Research Institute, 5-4-30 Moriyama, Moriyama, Shiga 524-8524, Japan.
Chio OkuyamaDivision of PET Imaging, Shiga Medical Center Research Institute, 5-4-30 Moriyama, Moriyama, Shiga 524-8524, Japan.
Masato HojoDepartment of Neurosurgery, Shiga Medical Center, 5-4-30 Moriyama, Moriyama, Shiga 524-8524, Japan.
Toshihiro MunemitsuDepartment of Neurosurgery, Shiga Medical Center, 5-4-30 Moriyama, Moriyama, Shiga 524-8524, Japan.
Masahiro SawadaDepartment of Neurosurgery, Shiga Medical Center, 5-4-30 Moriyama, Moriyama, Shiga 524-8524, Japan.
Masato KobayashiWellness Promotion Science Center, Institute of Medical, Kanazawa University, 5-10-80 Kodatsuno, Kanazawa, Ishikawa 920-0942, Japan.
Keiichi KawaiGraduate School of Health Sciences, College of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 5-10-80 Kodatsuno, Kanazawa, Ishikawa 920-0942, Japan.
Shigeki NagamachiDepartment of Radiology, Faculty of Medicine, University of Miyazaki, 5200 Kihara Kiyotake-cho, Miyazaki 889-1692, Japan.
Toshinori HiraiDepartment of Radiology, Faculty of Medicine, University of Miyazaki, 5200 Kihara Kiyotake-cho, Miyazaki 889-1692, Japan.
Susumu MiyamotoDepartment of Neurosurgery, Graduate School of Medicine, Kyoto University, 54 ShogoinKawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan.
Shiga Medical Center · JPKyoto University · JPUniversity of Miyazaki · JPKanazawa University · JPOtsu Red Cross Hospital · JPRakuwakai Otowa Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introductions: [ Methods: Thirty-one consecutive patients (male: 16, female: 15), who were suspected of having brain tumors, received both MeAIB-PET and MET-PET within a 2-week interval. All patients were classified into two groups: Group A as a benign group, which included patients who were diagnosed as low-grade astrocytoma, grade II or less, or other low-grade astrocytoma ( Results: In MeAIB-PET imaging, the SUVmax was 1.20 ± 1.29 for the benign group and 2.94 ± 1.22 for the malignant group ( Conclusions: MeAIB, a system A amino acid transport-specific radiolabeled agents, could provide better assessments for detecting malignant type brain tumors. In a differential diagnosis between low-grade and high-grade astrocytoma, MeAIB-PET is a useful diagnostic imaging tool, especially in evaluations using the Clinical trial registration: This trial was registered with UMIN000032498.

Indexed as

AdolescentAdultAgedAmino Acid Transport System AAstrocytomabeta-AlanineBrain NeoplasmsChildChild, PreschoolDiagnosis, DifferentialFemaleHumansMaleMethionineMiddle AgedPositron-Emission Tomography2,2-dimethyl-beta-alanineAmino Acid Transport System Abeta-Alaninecarbon-11 methionineMethionineRadiopharmaceuticals

Identifiers

PMID30026674
PMCPMC6031168
OpenAlexW2809431176

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.