Evidence map›Paper›PMID 30026563›Full record

ArticleScientific reports2018

Response Surface Methodology-Genetic Algorithm Based Medium Optimization, Purification, and Characterization of Cholesterol Oxidase from Streptomyces rimosus.

Akanksha Srivastava, Vineeta Singh, Shafiul Haque, Smriti Pandey, Manisha Mishra, Arshad Jawed, P K Shukla, P K Singh, C K M Tripathi

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 45 citations in OpenAlex.

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  7. A review of algorithmic approaches for cell culture media optimization.Frontiers in bioengineering and biotechnology · 2023
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  10. Optimization of β-1,4-Endoxylanase Production by anMolecules (Basel, Switzerland) · 2021
    Article
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  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Akanksha SrivastavaMicrobiology Division, CSIR-Central Drug Research Institute, Lucknow, 226031, India.
Vineeta SinghDepartment of Biotechnology, Institute of Engineering & Technology, Lucknow, 226021, Uttar Pradesh, India.
Shafiul HaqueResearch and Scientific Studies Unit, College of Nursing & Allied Health Sciences, Jazan University, Jazan, 45142, Saudi Arabia.
Smriti PandeyMicrobiology Division, CSIR-Central Drug Research Institute, Lucknow, 226031, India.
Manisha MishraPlant Molecular Biology Division, CSIR-National Botanical Research Institute, Lucknow, 226001, India.
Arshad JawedResearch and Scientific Studies Unit, College of Nursing & Allied Health Sciences, Jazan University, Jazan, 45142, Saudi Arabia.ORCID 0000-0002-3161-9864
P K ShuklaMicrobiology Division, CSIR-Central Drug Research Institute, Lucknow, 226031, India.
P K SinghPlant Molecular Biology Division, CSIR-National Botanical Research Institute, Lucknow, 226001, India.
C K M TripathiMicrobiology Division, CSIR-Central Drug Research Institute, Lucknow, 226031, India. ckm.tripathi@hotmail.com.
Central Drug Research Institute · INJazan University · SANational Botanical Research Institute · IN

Funding

Indian Council of Medical Research (ICMR) 45/09/2011
6 · The paper itself

Abstract

The applicability of the statistical tools coupled with artificial intelligence techniques was tested to optimize the critical medium components for the production of extracellular cholesterol oxidase (COD; an enzyme of commercial interest) from Streptomyces rimosus MTCC 10792. The initial medium component screening was performed using Placket-Burman design with yeast extract, dextrose, starch and ammonium carbonate as significant factors. Response surface methodology (RSM) was attempted to develop a statistical model with a significant coefficient of determination (R

Indexed as

AlgorithmsBacterial ProteinsCarbonatesCholesterol OxidaseEnzyme StabilityGlucoseModels, StatisticalMolecular WeightStarchStreptomyces rimosusammonium carbonateBacterial ProteinsCarbonatesCholesterol OxidaseGlucoseStarch

Identifiers

PMID30026563
PMCPMC6053457
OpenAlexW2884576567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.