ArticleScientific reports2018
Impact of honey on dental erosion and adhesion of early bacterial colonizers.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- A systematic review of interventions to mitigate radiotherapy-induced oral mucositis in head and neck cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Pooled it
- Trial
- Proteomic profile of the dentine pellicle modified with plant polyphenols and fluoride.Clinical oral investigations · 2026Article
- Review
- Honey Compounds Exhibit Antibacterial Effects AgainstAntibiotics (Basel, Switzerland) · 2025Article
- The Antibacterial Properties of Polish Honey againstAntibiotics (Basel, Switzerland) · 2023Article
- Antimicrobial Activity of Honey against Oral Microorganisms: Current Reality, Methodological Challenges and Solutions.Microorganisms · 2022Review
- Antibacterial and Antibiofilm Effect of Honey in the Prevention of Dental Caries: A Recent Perspective.Foods (Basel, Switzerland) · 2022Review
- Article
- Bee Venom, Honey, and Royal Jelly in the Treatment of Bacterial Infections of the Oral Cavity: A Review.Life (Basel, Switzerland) · 2021Review
- Efficacy of propolis in remineralising artificially induced demineralisation of human enamel - An in-vitro study.Journal of Taibah University Medical Sciences · 2021Article
- Polyphenols of Honeybee Origin with Applications in Dental Medicine.Antibiotics (Basel, Switzerland) · 2020Review
- Casein phosphopeptide combined with fluoride enhances the inhibitory effect on initial adhesion of Streptococcus mutans to the saliva-coated hydroxyapatite disc.BMC oral health · 2020Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim was to investigate if honey causes erosion and if salivary pellicle modified with honey, or its components, or the by-product propolis has a protective effect against dental erosion and adhesion of early bacterial colonizers. The tested substances were: 3 types of honey, methylglyoxal (MGO), hydrogen peroxide, propolis. First in the erosion experiment, 120 human enamel specimens were covered with salivary pellicle and modified with the substances. Then they were eroded with 1% citric acid, pH 3.6 for 2 min, before surface hardness was measured. In the microbiological assay, the enamel specimens (n = 126) covered with modified salivary pellicle were contaminated with bacterial suspensions. The antimicrobial activity of each substance and their effect on early bacterial colonizer adhesion and biofilm formation were determined. Despite a low pH, honey did not cause erosion. On the other hand, pellicle modification with the tested solutions did not protect the enamel from erosion. Microbiologically, the 3 honeys inhibited species-specific growth of oral bacteria. Propolis decreased initial attachment of Streptococcus gordonii, while one honey inhibited demineralization of enamel by biofilm. In conclusion, pellicle modification with honey, or its components, or propolis did neither protect against erosion nor promote it. Propolis presented some bacterial adhesion inhibition.
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Registered trials
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