Evidence map›Paper›PMID 30026512›Full record

ArticleScientific reports2018

Predictors of Early Onset Multiple Organ Dysfunction in Major Burn Patients with Ventilator Support: Experience from A Mass Casualty Explosion.

Jia-Yih Feng, Jung-Yien Chien, Kuo-Chin Kao, Cheng-Liang Tsai, Fang Ming Hung, Fan-Min Lin, Han-Chung Hu, Kun-Lun Huang, Chong-Jen Yu, Kuang-Yao Yang

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

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  10. Review
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  12. Burn care strategy in the covid-19 pandemic: a narrative review study.International journal of burns and trauma · 2021
    Review
  13. A case series of concomitant burn and COVID-19.Burns open : an international open access journal for burn injuries · 2021
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Jia-Yih FengDepartment of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.ORCID 0000-0001-8840-8112
Jung-Yien ChienDepartment of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.
Kuo-Chin KaoDepartment of Thoracic Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Cheng-Liang TsaiDivision of Pulmonary and Critical Care, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Fang Ming HungDepartment of Surgical Intensive Care Unit, Far Eastern Memorial Hospital, New Taipei, Taiwan.
Fan-Min LinDivision of Pulmonary Medicine, Department of Internal Medicine, Kaohsiung Armed Forces General Hospital, Kaohsiung, Taiwan.
Han-Chung HuDepartment of Thoracic Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Kun-Lun HuangGraduate Institute of Aerospace and Undersea Medicine, National Defense Medical Center, Taipei, Taiwan.
Chong-Jen YuDepartment of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.
Kuang-Yao YangDepartment of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan. kyyang@vghtpe.gov.tw.ORCID 0000-0002-2803-980X
Chang Gung University · TWNational Taiwan University Hospital · TWNational Yang Ming Chiao Tung University · TWFar Eastern Memorial Hospital · TWKaohsiung Armed Forces General Hospital · TWNational Defense Medical Center · TWTri-Service General Hospital · TW

Funding

Chang Gung Memorial Hospital, Linkou (Linkou Chang Gung Memorial Hospital) CORPG3F0091Chang Gung Memorial Hospital, Linkou (Linkou Chang Gung Memorial Hospital) CORPG3F0101
6 · The paper itself

Abstract

Organ dysfunction is common in patients with major burns and associated with poor outcomes. The risk factors for early onset multiple organ dysfunction syndrome (MODS) in major burn patients with invasive ventilator support has rarely been evaluated before. In this study, major burn patients with invasive ventilator support from 499 victims suffered in a mass casualty color dust explosion were retrospectively enrolled. The development of early MODS that occurred within 5 days after burn injury was determined and the risk factors associated with early MODS were analyzed. A total of 88 patients from five medical centers were included. Their mean total body surface area (TBSA) was 60.9 ± 15.8%, and 45 (51.1%) patients had early MODS. Hematologic failure was the most common organ failure (68.6%), followed by respiratory failure (48.9%). Independent clinical factors associated with early MODS included TBSA ≥55% (OR: 3.83; 95% CI: 1.29-11.37) and serum albumin level <2.1 g/dL upon admission (OR: 3.43; 95% CI: 1.01-11.57). Patients with early MODS had prolonged ventilator dependence and longer ICU admission than those without early MODS. Our results showed that early MODS in major burn patients with invasive ventilator support is very common and can be predicted early on admission.

Indexed as

AdolescentAdultBlast InjuriesBody Surface AreaBurnsExplosionsFemaleHumansIntensive Care UnitsLength of StayMaleMass Casualty IncidentsMultiple Organ FailureRetrospective StudiesRisk FactorsVentilators, Mechanical

Identifiers

PMID30026512
PMCPMC6053465
OpenAlexW2883001970

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.