Evidence map›Paper›PMID 30026261›Full record

ArticleBioscience reports2018

Effects of hypoxic preconditioning on neuroblastoma tumour oxygenation and metabolic signature in a chick embryo model.

Yousef K Al-Mutawa, Anne Herrmann, Catriona Corbishley, Paul D Losty, Marie Phelan, Violaine Sée

Open access · goldAbstract read
In one paragraph

Article in Bioscience reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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  7. Grading of endometrial cancer usingScientific reports · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yousef K Al-MutawaDepartment of Biochemistry, Institute of Integrated Biology, University of Liverpool, Liverpool L69 7ZB, U.K.
Anne HerrmannDepartment of Biochemistry, Institute of Integrated Biology, University of Liverpool, Liverpool L69 7ZB, U.K.
Catriona CorbishleyDepartment of Biochemistry, Institute of Integrated Biology, University of Liverpool, Liverpool L69 7ZB, U.K.
Paul D LostyAcademic Paediatric Surgery, Division of Child Health, University of Liverpool, Liverpool L12 2AP, U.K.
Marie PhelanDepartment of Biochemistry, Institute of Integrated Biology, University of Liverpool, Liverpool L69 7ZB, U.K. violaine@liverpool.ac.uk mphelan@liverpool.ac.uk.
Violaine SéeDepartment of Biochemistry, Institute of Integrated Biology, University of Liverpool, Liverpool L69 7ZB, U.K. violaine@liverpool.ac.uk mphelan@liverpool.ac.uk.
University of Liverpool · GB

Funding

Medical Research Council MR/M009114/1National Centre for the Replacement, Refinement and Reduction of Animals in Research NC/R001324/1
6 · The paper itself

Abstract

Hypoxia episodes and areas in tumours have been associated with metastatic dissemination and poor prognosis. Given the link between tumour tissue oxygen levels and cellular metabolic activity, we hypothesised that the metabolic profile between metastatic and non-metastatic tumours would reveal potential new biomarkers and signalling cues. We have used a previously established chick embryo model for neuroblastoma growth and metastasis, where the metastatic phenotype can be controlled by neuroblastoma cell hypoxic preconditioning (3 days at 1% O

Indexed as

MetabolomeAnimalsCell HypoxiaCell Line, TumorChick EmbryoDisease Models, AnimalHumansHypoxiaNeuroblastomaOxygenOxygencell cultureschick embryohypoxiaNMR spectroscopyoxygenationtumour biology

Identifiers

PMID30026261
PMCPMC6131206
OpenAlexW2883980984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.