Evidence map›Paper›PMID 30026259›Full record

ArticleClinical science (London, England : 1979)2018

Sex-dependent expression of brain medullary MAP and PI3 kinases in adult sheep with antenatal betamethasone exposure.

Alexa S Hendricks, Hossam A Shaltout, Brain M Westwood, Mark C Chappell, Debra I Diz

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical science (London, England : 1979), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Alexa S HendricksDepartment of Surgery, Hypertension and Vascular Research, Cardiovascular Sciences Center, Wake Forest University School of Medicine, Winston-Salem, NC, U.S.A.
Hossam A ShaltoutDepartment of Surgery, Hypertension and Vascular Research, Cardiovascular Sciences Center, Wake Forest University School of Medicine, Winston-Salem, NC, U.S.A.
Brain M WestwoodDepartment of Surgery, Hypertension and Vascular Research, Cardiovascular Sciences Center, Wake Forest University School of Medicine, Winston-Salem, NC, U.S.A.
Mark C ChappellDepartment of Surgery, Hypertension and Vascular Research, Cardiovascular Sciences Center, Wake Forest University School of Medicine, Winston-Salem, NC, U.S.A.
Debra I DizDepartment of Surgery, Hypertension and Vascular Research, Cardiovascular Sciences Center, Wake Forest University School of Medicine, Winston-Salem, NC, U.S.A. ddiz@wakehealth.edu.
Alexandria University · EG

Funding

The Impact of Antenatal Steroid Exposure on the Intrarenal Renin-Angiotensin SystP01HD047584 · NICHD · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ROSE, JAMES C. · 2005 to 2016
$13.0M
Deficiency in Angiotensin-(1-7) Alters Signaling Pathways Linked to ROS and NO in the BrainF99NS105212 · NINDS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HENDRICKS, ALEXA · 2017 to 2017
$45k
NICHD NIH HHS P01 HD047584NINDS NIH HHS F99 NS105212
6 · The paper itself

Abstract

Antenatal betamethasone (BM) therapy for women in jeopardy of premature delivery accelerates the lung development in preterm infants and reduces infant mortality rates, but may induce early programming events with chronic cardiovascular consequences. In a sheep model of fetal programming,

Indexed as

AnimalsBaroreflexBetamethasoneBlood PressureBrainFemaleFetal DevelopmentGlucocorticoidsHumansMalePhosphatidylinositol 3-KinasesPregnancyPrenatal Exposure Delayed EffectsSex FactorsSheepBetamethasoneGlucocorticoidsPhosphatidylinositol 3-Kinasesfetal programminghypertensionmitogen-activated protein kinasessex differences

Identifiers

PMID30026259
PMCPMC8459834
OpenAlexW2883889291

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.