Evidence map›Paper›PMID 30026237›Full record

ArticleThe Journal of experimental biology2018

Allosteric mechanisms underlying the adaptive increase in hemoglobin-oxygen affinity of the bar-headed goose.

Agnieszka Jendroszek, Hans Malte, Cathrine B Overgaard, Kristian Beedholm, Chandrasekhar Natarajan, Roy E Weber, Jay F Storz, Angela Fago

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of experimental biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 63 citations in OpenAlex.

  1. Gas exchange, oxygen transport and metabolism in high-altitude waterfowl.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Convergent High OAnimals : an open access journal from MDPI · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Changes in hemoglobin function and isoform expression during embryonic development in the American alligator,American journal of physiology. Regulatory, integrative and comparative physiology · 2021
    Article
  12. Comparison of hematological traits and oxygenation properties of hemoglobins from highland and lowland Asiatic toad (Bufo gargarizans).Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2021
    Review
  13. Article
  14. Evolved increases in hemoglobin-oxygen affinity and the Bohr effect coincided with the aquatic specialization of penguins.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  15. Physiological Genomics of Adaptation to High-Altitude Hypoxia.Annual review of animal biosciences · 2021
    Review
  16. Review
  17. Article
  18. Structure and function of crocodilian hemoglobins and allosteric regulation by chloride, ATP, and COAmerican journal of physiology. Regulatory, integrative and comparative physiology · 2020
    Article
  19. Article
  20. The Zebrafish CytochromeBiochemistry · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Agnieszka JendroszekDepartment of Bioscience, Aarhus University, DK-8000 Aarhus C, Denmark.ORCID 0000-0003-4299-4376
Hans MalteDepartment of Bioscience, Aarhus University, DK-8000 Aarhus C, Denmark.ORCID 0000-0003-3460-1819
Cathrine B OvergaardDepartment of Bioscience, Aarhus University, DK-8000 Aarhus C, Denmark.ORCID 0000-0002-8546-2735
Kristian BeedholmDepartment of Bioscience, Aarhus University, DK-8000 Aarhus C, Denmark.ORCID 0000-0001-5699-0849
Chandrasekhar NatarajanSchool of Biological Sciences, University of Nebraska, Lincoln, NE 68588, USA.ORCID 0000-0002-4841-0426
Roy E WeberDepartment of Bioscience, Aarhus University, DK-8000 Aarhus C, Denmark.ORCID 0000-0002-6865-441X
Jay F StorzSchool of Biological Sciences, University of Nebraska, Lincoln, NE 68588, USA.ORCID 0000-0001-5448-7924
Angela FagoDepartment of Bioscience, Aarhus University, DK-8000 Aarhus C, Denmark angela.fago@bios.au.dk.ORCID 0000-0001-7315-2628
Aarhus University · DKUniversity of Nebraska–Lincoln · US

Funding

Mutational Pleiotropy, Epistasis, and the Adaptive Evolution of Hemoglobin FunctionR01HL087216 · NHLBI · UNIVERSITY OF NEBRASKA LINCOLN · PI STORZ, JAY · 2008 to 2021
$4.5M
NHLBI NIH HHS R01 HL087216
6 · The paper itself

Abstract

The high blood-O

Indexed as

Adaptation, PhysiologicalAllosteric RegulationAltitudeAnimal MigrationAnimalsAnimals, WildAvian ProteinsGeeseHemoglobinsKineticsOxygenAvian ProteinsHemoglobinsOxygenAdaptationAllosteryBloodHigh-altitudeHypoxiaOxygen transport

Identifiers

PMID30026237
PMCPMC6176913
OpenAlexW2884927512

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.