Evidence map›Paper›PMID 30026190›Full record

ArticleCMAJ open

Presurgery osteoarthritis severity over 10 years in 2 Ontario prospective total knee replacement cohorts: a cohort study.

Aileen M Davis, Selahadin Ibrahim, Sheilah Hogg-Johnson, Dorcas E Beaton, Bert M Chesworth, Rajiv Gandhi, Nizar N Mahomed, Anthony V Perruccio, Vaishnav Rajgopal, Rosalind Wong and 1 more

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Article in CMAJ open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

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0 citing papers in PubMed, 1 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Aileen M DavisDivision of Health Care and Outcomes Research (Davis, Perruccio, Wong), Krembil Research Institute and Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto; Institute for Work and Health (Ibrahim, Beaton); Canadian Memorial Chiropractic College (Hogg-Johnson); Dalla Lana School of Public Health (Hogg-Johnson), University of Toronto; Institute of Health Policy, Management and Evaluation (Beaton), Dalla Lana School of Public Health, University of Toronto, Toronto, Ont.; Department of Physical Therapy (Chesworth), Western University, London, Ont.; Arthritis Program (Gandhi, Mahomed), Toronto Western Hospital and Division of Orthopaedic Surgery, University of Toronto, Toronto, Ont.; Orthopaedic Surgery (Rajgopal), Strathroy Middlesex General Hospital, Strathroy, Ont.; Division of Orthopaedic Surgery (Waddell), St. Michael's Hospital and University of Toronto, Toronto, Ont. adavis@uhnresearch.ca.
Selahadin IbrahimDivision of Health Care and Outcomes Research (Davis, Perruccio, Wong), Krembil Research Institute and Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto; Institute for Work and Health (Ibrahim, Beaton); Canadian Memorial Chiropractic College (Hogg-Johnson); Dalla Lana School of Public Health (Hogg-Johnson), University of Toronto; Institute of Health Policy, Management and Evaluation (Beaton), Dalla Lana School of Public Health, University of Toronto, Toronto, Ont.; Department of Physical Therapy (Chesworth), Western University, London, Ont.; Arthritis Program (Gandhi, Mahomed), Toronto Western Hospital and Division of Orthopaedic Surgery, University of Toronto, Toronto, Ont.; Orthopaedic Surgery (Rajgopal), Strathroy Middlesex General Hospital, Strathroy, Ont.; Division of Orthopaedic Surgery (Waddell), St. Michael's Hospital and University of Toronto, Toronto, Ont.
Sheilah Hogg-JohnsonDivision of Health Care and Outcomes Research (Davis, Perruccio, Wong), Krembil Research Institute and Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto; Institute for Work and Health (Ibrahim, Beaton); Canadian Memorial Chiropractic College (Hogg-Johnson); Dalla Lana School of Public Health (Hogg-Johnson), University of Toronto; Institute of Health Policy, Management and Evaluation (Beaton), Dalla Lana School of Public Health, University of Toronto, Toronto, Ont.; Department of Physical Therapy (Chesworth), Western University, London, Ont.; Arthritis Program (Gandhi, Mahomed), Toronto Western Hospital and Division of Orthopaedic Surgery, University of Toronto, Toronto, Ont.; Orthopaedic Surgery (Rajgopal), Strathroy Middlesex General Hospital, Strathroy, Ont.; Division of Orthopaedic Surgery (Waddell), St. Michael's Hospital and University of Toronto, Toronto, Ont.
Dorcas E BeatonDivision of Health Care and Outcomes Research (Davis, Perruccio, Wong), Krembil Research Institute and Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto; Institute for Work and Health (Ibrahim, Beaton); Canadian Memorial Chiropractic College (Hogg-Johnson); Dalla Lana School of Public Health (Hogg-Johnson), University of Toronto; Institute of Health Policy, Management and Evaluation (Beaton), Dalla Lana School of Public Health, University of Toronto, Toronto, Ont.; Department of Physical Therapy (Chesworth), Western University, London, Ont.; Arthritis Program (Gandhi, Mahomed), Toronto Western Hospital and Division of Orthopaedic Surgery, University of Toronto, Toronto, Ont.; Orthopaedic Surgery (Rajgopal), Strathroy Middlesex General Hospital, Strathroy, Ont.; Division of Orthopaedic Surgery (Waddell), St. Michael's Hospital and University of Toronto, Toronto, Ont.
Bert M ChesworthDivision of Health Care and Outcomes Research (Davis, Perruccio, Wong), Krembil Research Institute and Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto; Institute for Work and Health (Ibrahim, Beaton); Canadian Memorial Chiropractic College (Hogg-Johnson); Dalla Lana School of Public Health (Hogg-Johnson), University of Toronto; Institute of Health Policy, Management and Evaluation (Beaton), Dalla Lana School of Public Health, University of Toronto, Toronto, Ont.; Department of Physical Therapy (Chesworth), Western University, London, Ont.; Arthritis Program (Gandhi, Mahomed), Toronto Western Hospital and Division of Orthopaedic Surgery, University of Toronto, Toronto, Ont.; Orthopaedic Surgery (Rajgopal), Strathroy Middlesex General Hospital, Strathroy, Ont.; Division of Orthopaedic Surgery (Waddell), St. Michael's Hospital and University of Toronto, Toronto, Ont.
Rajiv GandhiDivision of Health Care and Outcomes Research (Davis, Perruccio, Wong), Krembil Research Institute and Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto; Institute for Work and Health (Ibrahim, Beaton); Canadian Memorial Chiropractic College (Hogg-Johnson); Dalla Lana School of Public Health (Hogg-Johnson), University of Toronto; Institute of Health Policy, Management and Evaluation (Beaton), Dalla Lana School of Public Health, University of Toronto, Toronto, Ont.; Department of Physical Therapy (Chesworth), Western University, London, Ont.; Arthritis Program (Gandhi, Mahomed), Toronto Western Hospital and Division of Orthopaedic Surgery, University of Toronto, Toronto, Ont.; Orthopaedic Surgery (Rajgopal), Strathroy Middlesex General Hospital, Strathroy, Ont.; Division of Orthopaedic Surgery (Waddell), St. Michael's Hospital and University of Toronto, Toronto, Ont.
Nizar N MahomedDivision of Health Care and Outcomes Research (Davis, Perruccio, Wong), Krembil Research Institute and Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto; Institute for Work and Health (Ibrahim, Beaton); Canadian Memorial Chiropractic College (Hogg-Johnson); Dalla Lana School of Public Health (Hogg-Johnson), University of Toronto; Institute of Health Policy, Management and Evaluation (Beaton), Dalla Lana School of Public Health, University of Toronto, Toronto, Ont.; Department of Physical Therapy (Chesworth), Western University, London, Ont.; Arthritis Program (Gandhi, Mahomed), Toronto Western Hospital and Division of Orthopaedic Surgery, University of Toronto, Toronto, Ont.; Orthopaedic Surgery (Rajgopal), Strathroy Middlesex General Hospital, Strathroy, Ont.; Division of Orthopaedic Surgery (Waddell), St. Michael's Hospital and University of Toronto, Toronto, Ont.
Anthony V PerruccioDivision of Health Care and Outcomes Research (Davis, Perruccio, Wong), Krembil Research Institute and Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto; Institute for Work and Health (Ibrahim, Beaton); Canadian Memorial Chiropractic College (Hogg-Johnson); Dalla Lana School of Public Health (Hogg-Johnson), University of Toronto; Institute of Health Policy, Management and Evaluation (Beaton), Dalla Lana School of Public Health, University of Toronto, Toronto, Ont.; Department of Physical Therapy (Chesworth), Western University, London, Ont.; Arthritis Program (Gandhi, Mahomed), Toronto Western Hospital and Division of Orthopaedic Surgery, University of Toronto, Toronto, Ont.; Orthopaedic Surgery (Rajgopal), Strathroy Middlesex General Hospital, Strathroy, Ont.; Division of Orthopaedic Surgery (Waddell), St. Michael's Hospital and University of Toronto, Toronto, Ont.
Vaishnav RajgopalDivision of Health Care and Outcomes Research (Davis, Perruccio, Wong), Krembil Research Institute and Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto; Institute for Work and Health (Ibrahim, Beaton); Canadian Memorial Chiropractic College (Hogg-Johnson); Dalla Lana School of Public Health (Hogg-Johnson), University of Toronto; Institute of Health Policy, Management and Evaluation (Beaton), Dalla Lana School of Public Health, University of Toronto, Toronto, Ont.; Department of Physical Therapy (Chesworth), Western University, London, Ont.; Arthritis Program (Gandhi, Mahomed), Toronto Western Hospital and Division of Orthopaedic Surgery, University of Toronto, Toronto, Ont.; Orthopaedic Surgery (Rajgopal), Strathroy Middlesex General Hospital, Strathroy, Ont.; Division of Orthopaedic Surgery (Waddell), St. Michael's Hospital and University of Toronto, Toronto, Ont.
Rosalind WongDivision of Health Care and Outcomes Research (Davis, Perruccio, Wong), Krembil Research Institute and Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto; Institute for Work and Health (Ibrahim, Beaton); Canadian Memorial Chiropractic College (Hogg-Johnson); Dalla Lana School of Public Health (Hogg-Johnson), University of Toronto; Institute of Health Policy, Management and Evaluation (Beaton), Dalla Lana School of Public Health, University of Toronto, Toronto, Ont.; Department of Physical Therapy (Chesworth), Western University, London, Ont.; Arthritis Program (Gandhi, Mahomed), Toronto Western Hospital and Division of Orthopaedic Surgery, University of Toronto, Toronto, Ont.; Orthopaedic Surgery (Rajgopal), Strathroy Middlesex General Hospital, Strathroy, Ont.; Division of Orthopaedic Surgery (Waddell), St. Michael's Hospital and University of Toronto, Toronto, Ont.
James P WaddellDivision of Health Care and Outcomes Research (Davis, Perruccio, Wong), Krembil Research Institute and Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto; Institute for Work and Health (Ibrahim, Beaton); Canadian Memorial Chiropractic College (Hogg-Johnson); Dalla Lana School of Public Health (Hogg-Johnson), University of Toronto; Institute of Health Policy, Management and Evaluation (Beaton), Dalla Lana School of Public Health, University of Toronto, Toronto, Ont.; Department of Physical Therapy (Chesworth), Western University, London, Ont.; Arthritis Program (Gandhi, Mahomed), Toronto Western Hospital and Division of Orthopaedic Surgery, University of Toronto, Toronto, Ont.; Orthopaedic Surgery (Rajgopal), Strathroy Middlesex General Hospital, Strathroy, Ont.; Division of Orthopaedic Surgery (Waddell), St. Michael's Hospital and University of Toronto, Toronto, Ont.
3M (United States) · USInstitute for Work and Health · CHInstitute for Work & Health · CAKrembil Research InstituteUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt has been suggested that total knee replacement is being performed in people with less-severe osteoarthritis. We aimed to determine whether there were differences in the presurgery profile, symptoms and disability of 2 cohorts who underwent total knee replacement over a 10-year period.

methodsPatients aged 18-85 years undergoing primary total knee replacement for osteoarthritis at 1 of 4 sites in Toronto and Strathroy, Ontario, were recruited in a cohort study during 2006-2008 (cohort 1) and 2012-2015 (cohort 2). Patients undergoing unicompartmental or revision arthroplasty were excluded. Demographic and health (body mass index [BMI], comorbidity) variables and osteoarthritis severity, as assessed with the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and the disability component of the Late-Life Function and Disability Instrument (LLFDI-D), were collected before surgery. We calculated proportions, means and standard deviations with 95% confidence intervals (CIs) for all data. We constructed density plots by tertile score for the WOMAC pain and physical function subscales and the LLFDI-D limitation scale.

resultsThere were 494 patients in cohort 1 and 251 patients in cohort 2. There were no differences in age, sex, education, living status, BMI, comorbidity, pain severity or disability between the cohorts based on overlapping 95% CIs and the density plots. More patients in cohort 1 than in cohort 2 were single (176 [35.6%], 95% CI 32.5%-41.1% v. 63 [25.1%], 95% CI 20.3%-31.0%). Patients in cohort 2 reported less limitation in higher-demand activities than did those in cohort 1 (mean score on LLFDI-D 62.3 [95% CI 60.7-63.9] v. 59.2 [95% CI 58.2-60.2]).

interpretationThe patient profile and reported osteoarthritis severity were similar in 2 cohorts that had total knee replacement over a 10-year period. This suggests that increasing total knee replacement volumes over this period likely were not driven by these factors.

Identifiers

PMID30026190
PMCPMC6182103
OpenAlexW2884197035

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.