ArticleBlood2018
Defective TAFI activation in hemophilia A mice is a major contributor to joint bleeding.
Article in Blood, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
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- Maladaptive lymphangiogenesis is associated with synovial iron accumulation and delayed clearance in factor VIII-deficient mice after induced hemarthrosis.Journal of thrombosis and haemostasis : JTH · 2023Article
- The potential role of protease systems in hemophilic arthropathy.Blood advances · 2022Article
- Hemophilic arthropathy: Current knowledge and future perspectives.Journal of thrombosis and haemostasis : JTH · 2021Review
- Characterization of Novel P-Selectin Targeted Complement Inhibitors in Murine Models of Hindlimb Injury and Transplantation.Frontiers in immunology · 2021Article
- Unique inflammatory signature in haemophilic arthropathy: miRNA changes due to interaction between blood and fibroblast-like synoviocytes.Journal of cellular and molecular medicine · 2020Article
- Activated platelet-based inhibition of fibrinolysis via thrombin-activatable fibrinolysis inhibitor activation system.Blood advances · 2020Article
- Illustrated State-of-the-Art Capsules of the ISTH 2020 Congress.Research and practice in thrombosis and haemostasis · 2020Article
- Article
- Plasminogen activation in the musculoskeletal acute phase response: Injury, repair, and disease.Research and practice in thrombosis and haemostasis · 2020Review
- Cardiac Myosin Promotes Thrombin Generation and Coagulation In Vitro and In Vivo.Arteriosclerosis, thrombosis, and vascular biology · 2020Article
- Role of thrombomodulin expression on hematopoietic stem cells.Journal of thrombosis and haemostasis : JTH · 2020Article
- Article
- Mechanisms of vascular permeability and remodeling associated with hemarthrosis in factor VIII-deficient mice.Journal of thrombosis and haemostasis : JTH · 2019Article
- TAFI deficiency causes maladaptive vascular remodeling after hemophilic joint bleeding.JCI insight · 2019Article
- Absence of functional compensation between coagulation factor VIII and plasminogen in double-knockout mice.Blood advances · 2018Article
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Authors and funding
7 authors at 4 institutions in 4 countries.
Funding
Abstract
Joint bleeds are common in congenital hemophilia but rare in acquired hemophilia A (aHA) for reasons unknown. To identify key mechanisms responsible for joint-specific bleeding in congenital hemophilia, bleeding phenotypes after joint injury and tail transection were compared in aHA wild-type (WT) mice (receiving an anti-factor VIII [FVIII] antibody) and congenital HA (FVIII
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.