Evidence map›Paper›PMID 30026182›Full record

ArticleBlood2018

Stella T Chou, Perry Evans, Sunitha Vege, Sarita L Coleman, David F Friedman, Margaret Keller, Connie M Westhoff

2 registry-linked trialsOpen access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Blood, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 63 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 1 pooled it
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04156893 phase1 / phase2recruitingnot on this mapstarted 2020, after this paper: background citation

RH Genotype Matched Red Cell Transfusions for Patients With Sickle Cell Disease

TypeinterventionalSponsorChildren's Hospital of PhiladelphiaRan2020 to 2029Enrolled35ConditionsSickle Cells DiseaseArmsRed cell units that are genotype matched at the RHD and RHCE loci
NCT04156906 early_phase1completednot on this mapstarted 2020, after this paper: background citation

RH Genotype Matched Red Cells for Patients With Sickle Cell Disease and Anti-D

TypeinterventionalSponsorChildren's Hospital of PhiladelphiaRan2020 to 2024Enrolled5ConditionsSickle Cell Disease, Anti-D AntibodiesArmsD+ RH genotype matched red cell units for transfusion
3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 1 synthesis or guideline pooled it, 118 citations in OpenAlex.

  1. Guideline
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  14. IntegratingMedicina (Kaunas, Lithuania) · 2025
    Article
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  19. Review
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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Stella T ChouDepartment of Pediatrics and.
Perry EvansDepartment of Biomedical and Health Informatics, The Children's Hospital of Philadelphia, Philadelphia, PA.ORCID 0000-0001-9391-2452
Sunitha VegeLaboratory of Immunohematology and Genomics, New York Blood Center, New York, NY.
Sarita L ColemanDepartment of Pediatrics and.
David F FriedmanDepartment of Pediatrics and.
Margaret KellerNational Molecular Laboratory at the American Red Cross, Philadelphia, PA.
Connie M WesthoffLaboratory of Immunohematology and Genomics, New York Blood Center, New York, NY.
Children's Hospital of Philadelphia · USNew York Blood Center · USAmerican Red Cross · US

Funding

Doris Duke Charitable Foundation 2011097Doris Duke Charitable Foundation 2015133
6 · The paper itself

Abstract

Rh alloimmunization remains a challenge for patients with sickle cell disease (SCD) despite transfusion of serologic Rh C, E, and K antigen-matched red cells. Inheritance of altered

Indexed as

AllelesGene FrequencyGenotypeAnemia, Sickle CellBlack or African AmericanBlood TransfusionFemaleHumansMaleRh-Hr Blood-Group SystemTransfusion ReactionWhite PeopleRHCE protein, humanRh-Hr Blood-Group SystemRho(D) antigen

Identifiers

PMID30026182
OpenAlexW2884541117

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.