Evidence map›Paper›PMID 30025885›Full record

ArticleEpidemics2019

Superensemble forecast of respiratory syncytial virus outbreaks at national, regional, and state levels in the United States.

Julia Reis, Teresa Yamana, Sasikiran Kandula, Jeffrey Shaman

Abstract read
In one paragraph

Article in Epidemics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Determining the timing of respiratory syncytial virus (RSV) epidemics: a systematic review, 2016 to 2021; method categorisation and identification of influencing factors.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Multi-faceted analysis and prediction for the outbreak of pediatric respiratory syncytial virus.Journal of the American Medical Informatics Association : JAMIA · 2023
    Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Julia ReisBiological Systems Engineering, Virginia Tech, Blacksburg, VA, United States. Electronic address: jreis@vt.edu.
Teresa YamanaDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, United States.
Sasikiran KandulaDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, United States.
Jeffrey ShamanDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, United States.

Funding

True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7M
Development and Dissemination of Operational Real-Time Respiratory Virus ForecastU01GM110748 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHAMAN, JEFFREY L · 2014 to 2018
$2.6M
Interdisciplinary Training in Climate and HealthT32ES023770 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHAMAN, JEFFREY L · 2014 to 2019
$1.5M
Influenza Outbreak Prediction: Applying Data Assimilation Methodology to Make...R01GM100467 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHAMAN, JEFFREY L · 2011 to 2015
$1.4M
NIEHS NIH HHS P30 ES009089NIEHS NIH HHS T32 ES023770NIGMS NIH HHS R01 GM100467NIGMS NIH HHS U01 GM110748
6 · The paper itself

Abstract

Respiratory syncytial virus (RSV) infections peak during the winter months in the United States, yet the timing, intensity, and onset of these outbreaks vary each year. An RSV vaccine is on the cusp of being released; precise models and accurate forecasts of RSV epidemics may prove vital for planning where and when the vaccine should be deployed. Accurate forecasts with sufficient spatial and temporal resolution could also be used to support the prevention or treatment of RSV infections. Previously, we developed and validated an RSV forecast system at the regional scale in the United States. This model-inference system had considerable forecast skill, relative to the historical expectance, for outbreak peak intensity, total outbreak size, and onset, but only marginal skill for predicting the timing of the outbreak peak. Here, we use a superensemble approach to combine three forecasting methods for RSV prediction in the US at three different spatial resolutions: national, regional, and state. At the regional and state levels, we find a substantial improvement of forecast skill, relative to historical expectance, for peak intensity, timing, and onset outbreak up to two months in advance of the predicted outbreak peak. Moreover, due to the greater variability of RSV outbreaks at finer spatial scales, we find that improvement of forecast skill at the state level exceeds that at the regional and national levels. Such finer scale superensemble forecasts may be more relevant for effecting local-scale interventions, particularly in communities with a high burden of RSV infection.

Indexed as

Bayes TheoremDisease OutbreaksForecastingHumansModels, BiologicalRespiratory Syncytial VirusesRespiratory Syncytial Virus InfectionsRetrospective StudiesSeasonsUnited StatesBayesian modelingComputational biologyEpidemicsForecastInfectious diseaseOutbreaksRSVSuperensemble

Identifiers

PMID30025885
PMCPMC7643169

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.