Evidence map›Paper›PMID 30025810›Full record

ReviewLancet (London, England)2018

Viral gastroenteritis.

Krisztián Bányai, Mary K Estes, Vito Martella, Umesh D Parashar

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Lancet (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 226 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
226citing papers in PubMed, 11 pooled it
21.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

226 citing papers in PubMed, 11 syntheses or guidelines pooled it, 457 citations in OpenAlex.

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166 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Krisztián BányaiInstitute for Veterinary Medical Research, Centre for Agricultural Research, Hungarian Academy of Sciences, Budapest, Hungary. Electronic address: bkrota@hotmail.com.
Mary K EstesDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.
Vito MartellaDepartment of Veterinary Medicine, University Aldo Moro of Bari, Provincial Road to Casamassima, Valenzano, Italy.
Umesh D ParasharViral Gastroenteritis Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Baylor College of Medicine · USCenters for Disease Control and Prevention · USUniversity of Bari Aldo Moro · IT

Funding

X-ray Crystallographic Studies on CalicivirusesP01AI057788 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI ATMAR, ROBERT L., ESTES, MARY KOLB · 2004 to 2024
$34.4M
Novel Platforms for Human Intestinal Enteroids: Matrix, Mechanics, and TopographyU19AI116497 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI GRANDE-ALLEN, KATHRYN JANE · 2015 to 2025
$13.2M
Regulation of Rotavirus ReplicationR01AI080656 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI Sue Ellen Crawford, Mary Kolb Estes · 2009 to 2026
$7.9M
Intestinal and Milk Glycan Expression in Restriction of Neonatal InfectionR01AI105101 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI ESTES, MARY KOLB · 2013 to 2016
$1.5M
Regulation of Rotavirus ReplicationR56AI080656 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI ESTES, MARY KOLB · 2014 to 2014
$433k
NIAID NIH HHS P01 AI057788NIAID NIH HHS R01 AI080656NIAID NIH HHS R01 AI105101NIAID NIH HHS R56 AI080656NIAID NIH HHS U19 AI116497NIH HHS AI057788NIH HHS AI080656NIH HHS AI105101
6 · The paper itself

Abstract

Enteric viruses, particularly rotaviruses and noroviruses, are a leading cause of gastroenteritis worldwide. Rotaviruses primarily affect young children, accounting for almost 40% of hospital admissions for diarrhoea and 200 000 deaths worldwide, with the majority of deaths occurring in developing countries. Two vaccines against rotavirus were licensed in 2006 and have been implemented in 95 countries as of April, 2018. Data from eight high-income and middle-income countries showed a 49-89% decline in rotavirus-associated hospital admissions and a 17-55% decline in all-cause gastroenteritis-associated hospital admissions among children younger than 5 years, within 2 years of vaccine introduction. Noroviruses affect people of all ages, and are a leading cause of foodborne disease and outbreaks of gastroenteritis worldwide. Prevention of norovirus infection relies on frequent hand hygiene, limiting contact with people who are infected with the virus, and disinfection of contaminated environmental surfaces. Norovirus vaccine candidates are in clinical trials; whether vaccines will provide durable protection against the range of genetically and antigenically diverse norovirus strains remains unknown. Treatment of viral gastroenteritis is based primarily on replacement of fluid and electrolytes.

Indexed as

AdolescentAdultAgedCaliciviridae InfectionsChildChild, PreschoolCross-Sectional StudiesDeveloping CountriesGastroenteritisHumansInfantMiddle AgedNorovirusPatient AdmissionRotavirus InfectionsRotavirus VaccinesRotavirus VaccinesViral Vaccines

Identifiers

PMID30025810
PMCPMC8883799
OpenAlexW4211103519

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.