Evidence map›Paper›PMID 30025540›Full record

ArticleBMC musculoskeletal disorders2018

Level of participation in physical therapy or an internet-based exercise training program: associations with outcomes for patients with knee osteoarthritis.

Megan Pignato, Liubov Arbeeva, Todd A Schwartz, Leigh F Callahan, Jennifer Cooke, Yvonne M Golightly, Adam P Goode, Bryan C Heiderscheit, Carla Hill, Kim M Huffman and 2 more

Registry-linked trialAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02312713 (Physical Therapy Versus Internet-Based Exercise Training for Patients With Knee Osteoarthritis), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02312713 nacompletednot on this map

Physical Therapy Versus Internet-Based Exercise Training for Patients With Knee Osteoarthritis

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2014 to 2017Enrolled350ConditionsKnee OsteoarthritisArmsInternet Based Exercise Training, Physical Therapy
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Megan PignatoUniversity of North Dakota School of Medicine and Health Sciences, 1301 N Columbia Rd, Grand Forks, ND, USA.
Liubov ArbeevaThurston Arthritis Research Center, University of North Carolina at Chapel Hill, 3300 Thurston Bldg., CB#, Chapel Hill, NC, 7280, USA.
Todd A SchwartzThurston Arthritis Research Center, University of North Carolina at Chapel Hill, 3300 Thurston Bldg., CB#, Chapel Hill, NC, 7280, USA.
Leigh F CallahanThurston Arthritis Research Center, University of North Carolina at Chapel Hill, 3300 Thurston Bldg., CB#, Chapel Hill, NC, 7280, USA.
Jennifer CookeDivision of Physical Therapy, Department of Allied Health Services, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Yvonne M GolightlyThurston Arthritis Research Center, University of North Carolina at Chapel Hill, 3300 Thurston Bldg., CB#, Chapel Hill, NC, 7280, USA.
Adam P GoodeDuke Clinical Research Institute, Durham, NC, USA.
Bryan C HeiderscheitDepartment of Orthopedics and Rehabilitation, University of Wisconsin-Madison, Madison, WI, USA.
Carla HillDivision of Physical Therapy, Department of Allied Health Services, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Kim M HuffmanDivision of Rheumatology, Department of Medicine, Duke University Medical Center, Durham, NC, USA.
Herbert H SeversonOregon Research Institute, Eugene, OR, USA.
Kelli D AllenThurston Arthritis Research Center, University of North Carolina at Chapel Hill, 3300 Thurston Bldg., CB#, Chapel Hill, NC, 7280, USA. kdallen@email.unc.edu.

Funding

UNC-CH Summer Research Training in Aging for Medical StudentsT35AG038047 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JAN BUSBY-WHITEHEAD · 2010 to 2026
$1.4M
NIAMS NIH HHS P60 AR062760NIA NIH HHS T35 AG038047NIA NIH HHS T35-AG038047-08Patient-Centered Outcomes Research Institute CER-1306-02043U.S. Department of Veterans Affairs CIN 13-410
6 · The paper itself

Abstract

backgroundTo examine whether number of physical therapy (PT) visits or amount of use of an internet-based exercise training (IBET) program is associated with differential improvement in outcomes for participants with knee osteoarthritis (OA).

methodsA secondary analysis was performed using data from participants in 2 arms of a randomized control trial for individuals with symptomatic knee OA: PT (N = 135) or IBET (N = 124). We examined associations of number of PT visits attended (up to 8) or number of days the IBET website was accessed during the initial 4-month study period with changes in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) total, pain and function subscales, as well as a 2-min Step Test, at 4-month and 12-month follow-up.

resultsParticipants with more PT visits experienced greater improvement in WOMAC total score (estimate per additional visit = - 1.18, CI 95% = - 1.91, 0.46, p <  0.001) and function subscore (estimate = - 0.80, CI 95% = - 1.33, - 0.28, p <  0.001) across follow-up periods. For WOMAC pain subscale, the association with number of PT visits varied significantly between 4- and 12-month follow-up, with a stronger relationship at 4-months. There was a non-significant trend for more PT visits to be associated with greater improvement in 2-min Step Test. More frequent use of the IBET website was not associated with greater improvement for any outcome, at either time point.

conclusionIncreased number of PT visits was associated with improved outcomes, and some of this benefit persisted 8 months after PT ended. This provides guidance for PT clinical practice and policies.

trial registrationNCT02312713 , posted 9/25/2015.

Indexed as

AgedExerciseFemaleFollow-Up StudiesHumansInternetMaleMiddle AgedOsteoarthritis, KneePatient ParticipationPhysical Therapy ModalitiesSelf EfficacyTherapy, Computer-AssistedTreatment OutcomeExerciseOsteoarthritisPhysical therapy

Identifiers

PMID30025540
PMCPMC6053740

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.