Evidence map›Paper›PMID 30025530›Full record

Observational studyBMC pediatrics2018

The CANadian Pediatric Weight management Registry (CANPWR): lessons learned from developing and initiating a national, multi-centre study embedded in pediatric clinical practice.

Katherine M Morrison, Geoff D C Ball, Josephine Ho, Pam Mackie, Annick Buchholz, Jean-Pierre Chanoine, Jill Hamilton, Anne-Marie Laberge, Laurent Legault, Lehana Thabane and 2 more

Abstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Child and adolescent obesity.Nature reviews. Disease primers · 2023
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Katherine M MorrisonDepartment of Pediatrics, McMaster University, Hamilton, ON, Canada. kmorrison@mcmaster.ca.ORCID 0000-0002-1737-256X
Geoff D C BallDepartment of Pediatrics, University of Alberta, Edmonton, AB, Canada.
Josephine HoDepartment of Pediatrics, University of Calgary, Calgary, AB, Canada.
Pam MackiePopulation Health Research Institute, McMaster University, Hamilton, ON, Canada.
Annick BuchholzChildren's Hospital of Eastern Ontario, Ottawa, ON, Canada.
Jean-Pierre ChanoineDepartment of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
Jill HamiltonThe Hospital for Sick Children, Toronto, ON, Canada.
Anne-Marie LabergeDepartment of Pediatrics, CHU Ste Justine, Montreal, QC, Canada.
Laurent LegaultDepartment of Pediatrics, McGill University, Montreal, QC, Canada.
Lehana ThabaneDepartment of Pediatrics, McMaster University, Hamilton, ON, Canada.
Mark TremblayChildren's Hospital of Eastern Ontario, Ottawa, ON, Canada.
Ian ZenleaCredit Valley Hospital, Mississauga, ON, Canada.

Funding

CIHR 120287CIHR FRN 123505
6 · The paper itself

Abstract

backgroundThere is increasing recognition of the value of "real-world evidence" in evaluating health care services. Registry-based, observational studies conducted in clinical settings represent a relevant model to achieve this directive. Starting in 2010, we undertook a longitudinal, observational study (the CANadian Pediatric Weight management Registry [CANPWR]), which is embedded in 10 multidisciplinary, pediatric weight management clinics across Canada. The objective of this paper was to share the lessons our team learned from this multi-centre project.

methodsData sources included a retrospective review of minutes from 120 teleconferences with research staff and investigators, notes taken during clinical site visits made by project leaders, information from quality control processes to ensure data accuracy and completeness, and a study-specific survey that was sent to all sites to solicit feedback from research team members (n = 9). Through an iterative process, the writing group identified key themes that surfaced during review of these information sources and final lessons learned were developed.

resultsSeveral key lessons emerged from our research, including the (1) value of pilot studies and central research coordination, (2) need for effective and regular communication, (3) importance of consensus on determining outcome measures, (4) challenge of embedding research within clinical practice, and (5) difficulty in recruiting and retaining participants. The sites were, in spite of these challenges, enthusiastic about the benefits of participating in multi-centre collaborative studies.

conclusionDespite some challenges, multi-centre observational studies embedded in pediatric weight management clinics are feasible and can contribute important, practical insights into the effectiveness of health services for managing pediatric obesity in real-world settings.

Indexed as

RegistriesCanadaChildChild Health ServicesCommunicationConsensusHumansLongitudinal StudiesPatient SelectionPediatric ObesityPilot ProjectsProspective StudiesTranslational Research, BiomedicalWeight Reduction ProgramsCardiometabolic health outcomesChildhood obesityCohort studyPediatricResearch methodologyTreatmentWeight management

Identifiers

PMID30025530
PMCPMC6053829

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.