ArticleInvestigative ophthalmology & visual science2018
Projection-Resolved OCT Angiography of Microvascular Changes in Paracentral Acute Middle Maculopathy and Acute Macular Neuroretinopathy.
Article in Investigative ophthalmology & visual science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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Who cites it
51 citing papers in PubMed, 100 citations in OpenAlex.
- Evaluation of retinal microvasculature in exotropia with abnormal binocular vision by optical coherence tomography angiography.BMC ophthalmology · 2023Trial
- Acute macular neuroretinopathy: is the name still appropriate?Medical hypothesis, discovery & innovation ophthalmology journal · 2026Review
- Correlation of Structure With Function: Future Utilities for Optical Coherence Tomography Angiography in Neuro-Ophthalmology.Clinical & experimental ophthalmology · 2025Review
- Acute macular neuroretinopathy after Covid 19 in an eye with a congenital retinal macrovessel - a case report.American journal of ophthalmology case reports · 2025Article
- The characteristics of multimodal fundus imaging in AMN patients following COVID infection.Scientific reports · 2025Article
- Paracentral Acute Middle Maculopathy (PAMM) in Ocular Vascular Diseases-What We Know and Future Perspectives.Vision (Basel, Switzerland) · 2025Review
- Extramacular paracentral acute middle maculopathy-like retinal ischemia after vitrectomy for epiretinal membrane.American journal of ophthalmology case reports · 2024Article
- Optical coherence tomography angiography suggests choriocapillaris perfusion deficit as etiology of acute macular neuroretinopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Type II Acute Macular Neuroretinopathy Secondary to Malaria.Case reports in ophthalmological medicine · 2024Article
- Retinal Findings and Cardiovascular Risk: Prognostic Conditions, Novel Biomarkers, and Emerging Image Analysis Techniques.Journal of personalized medicine · 2023Review
- Swept-source optical coherence tomography angiography metrics of retinal ischaemic perivascular lesions in patients being evaluated for carotid artery stenosis and controls.BMJ open ophthalmology · 2023Article
- Concomitant paracentral acute middle maculopathy and acute macular neuroretinopathy in eyes post-blunt trauma.Indian journal of ophthalmology · 2023Article
- A Case of Concurrent Acute Macular Neuroretinopathy and Paracentral Acute Middle Maculopathy Following Pfizer-BioNTech COVID-19 Vaccination.Turkish journal of ophthalmology · 2023Article
- Optical Coherence Tomography Angiography of Volumetric Arteriovenous Relationships in the Healthy Macula and Their Derangement in Disease.Investigative ophthalmology & visual science · 2023Article
- Article
- Paracentral Acute Middle Maculopathy As the Presenting Sign of Ischemic Cardiomyopathy.Cureus · 2023Article
- Parafoveal acute middle maculopathy (PAMM) in sickle cell disease after discontinuation of hydroxyurea.American journal of ophthalmology case reports · 2022Article
- Acute macular neuroretinopathy associated with intravitreal anti-VEGF injection: A case report.American journal of ophthalmology case reports · 2022Article
- Deep Capillary Plexus Features in Acute Macular Neuroretinopathy: Novel Insights Based on the Anatomy of Henle Fiber Layer.Investigative ophthalmology & visual science · 2022Article
- Ischemic retinal events after COVID-19 vaccination.American journal of ophthalmology case reports · 2022Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Purpose: To identify the microvascular changes associated with paracentral acute middle maculopathy (PAMM) and acute macular neuroretinopathy (AMN) and to improve our understanding of the relevant involvement of the three retinal capillary plexuses using projection-resolved optical coherence tomography angiography (PR-OCTA). Methods: This was a retrospective study of 18 eyes with AMN or PAMM imaged with OCTA. We used cross-sectional PR-OCTA to localize reduced flow signal to the superficial (SCP), middle (MCP), or deep capillary plexus (DCP) or choriocapillaris that corresponded to inner retinal PAMM or outer retinal AMN lesions on OCT. Results: Five eyes with AMN showed outer retinal disruption on OCT associated with reduced DCP flow signal. All three eyes with AMN and follow-up had recovery of DCP flow. Thirteen eyes with PAMM showed middle retinal disruption on OCT associated with reduced flow signal in both the MCP and DCP. Of these, five also had reduced flow signal in the SCP. All 10 eyes with PAMM and follow-up showed variable recovery of flow signal in one or more plexuses. PAMM reperfusion was primarily arterial in nature. Three eyes with PAMM and no evidence of MCP reperfusion experienced severe thinning of the inner nuclear layer (INL), while seven eyes with robust MCP flow signal recovery showed relative preservation of INL thickness. Conclusions: Using PR-OCTA, we found that AMN was associated with reduced DCP flow signal, while PAMM was associated with reduced MCP and DCP flow signal and occasionally the SCP. The MCP appears to be important in sustaining INL thickness in these eyes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.