Evidence map›Paper›PMID 30024862›Full record

ArticleJournal of pediatric gastroenterology and nutrition2018

Preparation of Powdered Infant Formula: Could Product's Safety Be Improved?

Marina Nadia Losio, Enrico Pavoni, Guido Finazzi, Carlo Agostoni, Paolo Daminelli, Elena Dalzini, Giorgio Varisco, Stefano Cinotti

Abstract read
In one paragraph

Article in Journal of pediatric gastroenterology and nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Probiotics as a Barrier AgainstFoods (Basel, Switzerland) · 2026
    Article
  2. Inactivation kinetics ofFrontiers in microbiology · 2026
    Article
  3. Article
  4. Article
  5. Inactivation ofFood science and biotechnology · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Determination of 40 Elements in Powdered Infant Formulas and Related Risk Assessment.International journal of environmental research and public health · 2021
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marina Nadia LosioIstituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "B. Ubertini," Brescia.
Enrico PavoniIstituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "B. Ubertini," Brescia.
Guido FinazziIstituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "B. Ubertini," Brescia.
Carlo AgostoniPediatric Intermediate Care Unit, Fondazione IRCCS "Ca' Granda" Ospedale Maggiore Policlinico, DISCCO, University of Milan, Milan, Italy.
Paolo DaminelliIstituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "B. Ubertini," Brescia.
Elena DalziniIstituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "B. Ubertini," Brescia.
Giorgio VariscoIstituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "B. Ubertini," Brescia.
Stefano CinottiIstituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "B. Ubertini," Brescia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recent outbreak of Salmonella Agona linked to the consumption of infant formula (powdered formula) has rekindled the attention about the correct procedures for preparation and use of these products. International guidelines have already been published so far, particularly in association with Cronobacter sakazakii in early 2000s. FAO/WHO suggested to reconstitute formula with water at no less than 70°C. We therefore contaminated powdered formula with low levels of Salmonella spp and C sakazakii to evaluate the pathogens inactivation during the formula preparation using water at 70°C. In these conditions we observed a survival of both pathogens, indicating that the suggested recommendations may be not enough to guarantee the safety of this product. Higher temperatures are needed to reduce the biological risk, even if it may be not easily realized in actual domestic conditions. Moreover, the impact on the nutritional value of reconstituted formulas should be evaluated.

Indexed as

Food MicrobiologyCronobacterFemaleFood ContaminationFood HandlingHumansInfantInfant FormulaInfant, NewbornMalePowdersSalmonellaTemperatureWaterPowdersWater

Identifiers

PMID30024862
PMCPMC6155361

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.