Evidence map›Paper›PMID 30024804›Full record

ArticleAmerican journal of public health2018

Evaluating Public Health Interventions: 8. Causal Inference for Time-Invariant Interventions.

Donna Spiegelman, Xin Zhou

Open access · greenAbstract read
In one paragraph

Article in American journal of public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Observational
  2. Navigating grey areas in HIV and mental health implementation science.Journal of the International AIDS Society · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Donna SpiegelmanDonna Spiegelman is with the departments of Epidemiology, Biostatistics, Nutrition, and Global Health, Harvard T. H. Chan School of Public Health, Boston, MA. Xin Zhou is with the departments of Epidemiology and Biostatistics, Harvard T. H. Chan School of Public Health.
Xin ZhouDonna Spiegelman is with the departments of Epidemiology, Biostatistics, Nutrition, and Global Health, Harvard T. H. Chan School of Public Health, Boston, MA. Xin Zhou is with the departments of Epidemiology and Biostatistics, Harvard T. H. Chan School of Public Health.
Harvard University · US

Funding

Comprehensive Translational Science Analytics Tools for the Global Health AgendaDP1ES025459 · NIEHS · YALE UNIVERSITY · PI SPIEGELMAN, DONNA L · 2014 to 2018
$4.1M
NIEHS NIH HHS DP1 ES025459
6 · The paper itself

Abstract

We provide an overview of classical and newer methods for the control of confounding of time-invariant interventions to permit causal inference in public health evaluations. We estimated the causal effect of gender on all-cause mortality in a large HIV care and treatment program supported by the President's Emergency Program for AIDS Relief in Dar es Salaam, Tanzania, between 2004 and 2012. We compared results from multivariable modeling, three propensity score methods, inverse-probability weighting, doubly robust methods, and targeted maximum likelihood estimation. Considerable confounding was evident, and, as expected by theory, all methods considered gave the same result, a statistically significant approximately 20% increased mortality rate in men. In general, there is no clear advantage of any of these methods for causal inference over classical multivariable modeling, from the point of view of either bias reduction or efficiency. Rather, given sufficient data to adequately fit the multivariable model to the data, multivariable modeling will yield causal estimates with the greatest statistical efficiency. All methods can adjust only for well-measured confounders-if there are unmeasured or poorly measured confounders, none of these methods will yield causal estimates.

Indexed as

CausalityProgram EvaluationPublic HealthConfounding Factors, EpidemiologicFemaleHIV InfectionsHumansMaleMortality, PrematureProportional Hazards ModelsSex Factors

Identifiers

PMID30024804
PMCPMC6085031
OpenAlexW2883925922

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.