Evidence map›Paper›PMID 30024802›Full record

ArticleAmerican journal of public health2018

HIV Preexposure Prophylaxis as a Gateway to Primary Care.

Julia L Marcus, Kenneth Levine, Chris Grasso, Douglas S Krakower, Victoria Powell, Kyle T Bernstein, Stephen Boswell, Kenneth H Mayer

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 43 citations in OpenAlex.

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  10. Pre-exposure prophylaxis as an opportunity for engagement in HIV prevention among South African adolescents.SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance · 2022
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  19. Pre-exposure prophylaxis and primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2020
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Julia L MarcusJulia L. Marcus is with the Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA. Kenneth Levine, Chris Grasso, Douglas S. Krakower, Victoria Powell, Stephen Boswell, and Kenneth H. Mayer are with the Fenway Institute, Fenway Health, Boston, MA. Kyle T. Bernstein is with the Centers for Disease Control and Prevention, Atlanta, GA.
Kenneth LevineJulia L. Marcus is with the Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA. Kenneth Levine, Chris Grasso, Douglas S. Krakower, Victoria Powell, Stephen Boswell, and Kenneth H. Mayer are with the Fenway Institute, Fenway Health, Boston, MA. Kyle T. Bernstein is with the Centers for Disease Control and Prevention, Atlanta, GA.
Chris GrassoJulia L. Marcus is with the Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA. Kenneth Levine, Chris Grasso, Douglas S. Krakower, Victoria Powell, Stephen Boswell, and Kenneth H. Mayer are with the Fenway Institute, Fenway Health, Boston, MA. Kyle T. Bernstein is with the Centers for Disease Control and Prevention, Atlanta, GA.
Douglas S KrakowerJulia L. Marcus is with the Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA. Kenneth Levine, Chris Grasso, Douglas S. Krakower, Victoria Powell, Stephen Boswell, and Kenneth H. Mayer are with the Fenway Institute, Fenway Health, Boston, MA. Kyle T. Bernstein is with the Centers for Disease Control and Prevention, Atlanta, GA.
Victoria PowellJulia L. Marcus is with the Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA. Kenneth Levine, Chris Grasso, Douglas S. Krakower, Victoria Powell, Stephen Boswell, and Kenneth H. Mayer are with the Fenway Institute, Fenway Health, Boston, MA. Kyle T. Bernstein is with the Centers for Disease Control and Prevention, Atlanta, GA.
Kyle T BernsteinJulia L. Marcus is with the Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA. Kenneth Levine, Chris Grasso, Douglas S. Krakower, Victoria Powell, Stephen Boswell, and Kenneth H. Mayer are with the Fenway Institute, Fenway Health, Boston, MA. Kyle T. Bernstein is with the Centers for Disease Control and Prevention, Atlanta, GA.
Stephen BoswellJulia L. Marcus is with the Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA. Kenneth Levine, Chris Grasso, Douglas S. Krakower, Victoria Powell, Stephen Boswell, and Kenneth H. Mayer are with the Fenway Institute, Fenway Health, Boston, MA. Kyle T. Bernstein is with the Centers for Disease Control and Prevention, Atlanta, GA.
Kenneth H MayerJulia L. Marcus is with the Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA. Kenneth Levine, Chris Grasso, Douglas S. Krakower, Victoria Powell, Stephen Boswell, and Kenneth H. Mayer are with the Fenway Institute, Fenway Health, Boston, MA. Kyle T. Bernstein is with the Centers for Disease Control and Prevention, Atlanta, GA.
Harvard Pilgrim Health Care · US

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI RAJESH T GANDHI · 2004 to 2026
$94.4M
Optimizing HIV Pre-Exposure Prophylaxis through Shared Decision MakingK23MH098795 · NIMH · BETH ISRAEL DEACONESS MEDICAL CENTER · PI KRAKOWER, DOUGLAS SCOTT · 2012 to 2016
$873k
Optimizing Care for HIV/HCV-Coinfected Patients in the New HCV Treatment EraK01AI122853 · NIAID · KAISER FOUNDATION RESEARCH INSTITUTE · PI MARCUS, JULIA L. · 2016 to 2020
$655k
NIAID NIH HHS K01 AI122853NIAID NIH HHS P30 AI060354NIMH NIH HHS K23 MH098795
6 · The paper itself

Abstract

objectivesTo determine whether HIV preexposure prophylaxis (PrEP) use is associated with use of non-HIV-related health care.

methodsWe conducted a cross-sectional study of potential PrEP candidates at a Boston, Massachusetts, community health clinic during 2012 to 2016, comparing the proportion of PrEP users and non-PrEP users receiving primary care.

resultsOf 5857 PrEP candidates, 2047 (35%) were prescribed PrEP. After adjustment for demographics and number of visits, more PrEP users received influenza vaccination (prevalence ratio [PR] = 1.28; 95% confidence interval [CI] = 1.20, 1.37), tobacco screening (PR = 1.06; 95% CI = 1.02, 1.09), and depression screening (PR = 1.07; 95% CI = 1.04, 1.11) compared with non-PrEP users. After additional adjustment for diabetes, hypertension, and overweight or obesity, more PrEP users received glucose testing (PR = 1.64; 95% CI = 1.56, 1.72) but fewer received hemoglobin A1c testing (PR = 0.81; 95% CI = 0.71, 0.93) compared with non-PrEP users.

conclusionsPrEP use was associated with receipt of influenza vaccination, tobacco and depression screening, and glucose but not hemoglobin A1c testing. Among PrEP users receiving routine care, the benefits of PrEP may extend to behavioral health, mental health, and prevention and treatment of other infectious and chronic diseases.

Indexed as

Pre-Exposure ProphylaxisAdultAmbulatory Care FacilitiesAnti-HIV AgentsBostonCross-Sectional StudiesDepressionDiabetes MellitusFemaleHIV InfectionsHumansInfluenza VaccinesMaleMass ScreeningPrimary Health CareTobacco Use DisorderAnti-HIV AgentsInfluenza Vaccines

Identifiers

PMID30024802
PMCPMC6137783
OpenAlexW2884695578

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.